Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia
The association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism with plasma ACE, renin activity and endothelial function of skin microvassals were studied. Preeclamptic patients with the DD genotype of ACE I/D gene polymorphism have lowest plasma renin activity leve...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2011-08-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1423 |
| _version_ | 1797873028718133248 |
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| author | O. V. Radkov M. N. Kalinkin V. V. Zavarin |
| author_facet | O. V. Radkov M. N. Kalinkin V. V. Zavarin |
| author_sort | O. V. Radkov |
| collection | DOAJ |
| description | The association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism with plasma ACE, renin activity and endothelial function of skin microvassals were studied. Preeclamptic patients with the DD genotype of ACE I/D gene polymorphism have lowest plasma renin activity level and endothelium-dependent vasodilatation, D allele carriers have highest plasma ACE activity. |
| first_indexed | 2024-04-10T01:09:41Z |
| format | Article |
| id | doaj.art-530acf7ad1944cef873859374afc3bd4 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:09:41Z |
| publishDate | 2011-08-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-530acf7ad1944cef873859374afc3bd42023-03-13T09:58:15ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-08-01104323610.20538/1682-0363-2011-4-32-36934Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsiaO. V. Radkov0M. N. Kalinkin1V. V. Zavarin2Тверская государственная медицинская академияТверская государственная медицинская академияТверская государственная медицинская академияThe association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism with plasma ACE, renin activity and endothelial function of skin microvassals were studied. Preeclamptic patients with the DD genotype of ACE I/D gene polymorphism have lowest plasma renin activity level and endothelium-dependent vasodilatation, D allele carriers have highest plasma ACE activity.https://bulletin.ssmu.ru/jour/article/view/1423гестозэндотелиальная дисфункцияангиотензинпревращающий ферментренинполиморфизм генов |
| spellingShingle | O. V. Radkov M. N. Kalinkin V. V. Zavarin Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia Бюллетень сибирской медицины гестоз эндотелиальная дисфункция ангиотензинпревращающий фермент ренин полиморфизм генов |
| title | Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia |
| title_full | Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia |
| title_fullStr | Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia |
| title_full_unstemmed | Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia |
| title_short | Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia |
| title_sort | association of insertion deletion polymorphism of the ace gene with factors of circulating rennin angiotensin aldosterone system and endothelial function of skin microvassals in preeclampsia |
| topic | гестоз эндотелиальная дисфункция ангиотензинпревращающий фермент ренин полиморфизм генов |
| url | https://bulletin.ssmu.ru/jour/article/view/1423 |
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