Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic Review
Bone marrow (BM) has been regarded as the primarily source of hematopoietic stem cells for many years. Recent researches have shown BM contains not only hematopoietic but also heterogeneous non-hematopoietic stem cells. Till now, similar or overlapping isolation strategies of primitive non-hematopoi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Fasa University of Medical Sciences
2016-12-01
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| Series: | Journal of Advanced Biomedical Sciences |
| Subjects: | |
| Online Access: | http://jabs.fums.ac.ir/article-1-1096-en.pdf |
| _version_ | 1797679620065067008 |
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| author | Samad Nadri Ehsan Saburi Parisa Nadri Ghasem Brati |
| author_facet | Samad Nadri Ehsan Saburi Parisa Nadri Ghasem Brati |
| author_sort | Samad Nadri |
| collection | DOAJ |
| description | Bone marrow (BM) has been regarded as the primarily source of hematopoietic stem cells for many years. Recent researches have shown BM contains not only hematopoietic but also heterogeneous non-hematopoietic stem cells. Till now, similar or overlapping isolation strategies of primitive non-hematopoietic stem cells in BM were named by different investigators and hence were assigned different names (e.g. mesenchymal stem cells, or multipotent adult progenitor cells) from alternative sources and different animal species. The differentiation potential of these cells to mesenchymal lineages has generated a great deal of interest in regenerative medicine and tissue engineering. Murine Mesenchymal stem cells (mMSCs) are appropriate models for preclinical investigations on human cell therapies. The isolation of BM-derived mMSCs is discussed as an unresolved issue in mesenchymal stem cells researches. The objective of the present review is the description of multiple methodological approaches to isolate mMSCs. |
| first_indexed | 2024-03-11T23:17:26Z |
| format | Article |
| id | doaj.art-530af17682f841fca703aa4c88677231 |
| institution | Directory Open Access Journal |
| issn | 2228-5105 2783-1523 |
| language | English |
| last_indexed | 2024-03-11T23:17:26Z |
| publishDate | 2016-12-01 |
| publisher | Fasa University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Biomedical Sciences |
| spelling | doaj.art-530af17682f841fca703aa4c886772312023-09-20T21:22:32ZengFasa University of Medical SciencesJournal of Advanced Biomedical Sciences2228-51052783-15232016-12-0164417425Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic ReviewSamad Nadri0Ehsan Saburi1Parisa Nadri2Ghasem Brati3 Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Isfahan University of technology, Isfahan,Iran Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Bone marrow (BM) has been regarded as the primarily source of hematopoietic stem cells for many years. Recent researches have shown BM contains not only hematopoietic but also heterogeneous non-hematopoietic stem cells. Till now, similar or overlapping isolation strategies of primitive non-hematopoietic stem cells in BM were named by different investigators and hence were assigned different names (e.g. mesenchymal stem cells, or multipotent adult progenitor cells) from alternative sources and different animal species. The differentiation potential of these cells to mesenchymal lineages has generated a great deal of interest in regenerative medicine and tissue engineering. Murine Mesenchymal stem cells (mMSCs) are appropriate models for preclinical investigations on human cell therapies. The isolation of BM-derived mMSCs is discussed as an unresolved issue in mesenchymal stem cells researches. The objective of the present review is the description of multiple methodological approaches to isolate mMSCs.http://jabs.fums.ac.ir/article-1-1096-en.pdfmurine mesenchymal stem cellsbone marrowisolation |
| spellingShingle | Samad Nadri Ehsan Saburi Parisa Nadri Ghasem Brati Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic Review Journal of Advanced Biomedical Sciences murine mesenchymal stem cells bone marrow isolation |
| title | Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic Review |
| title_full | Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic Review |
| title_fullStr | Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic Review |
| title_full_unstemmed | Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic Review |
| title_short | Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic Review |
| title_sort | isolation methods of mesenchymal stem cells in mice a systematic review |
| topic | murine mesenchymal stem cells bone marrow isolation |
| url | http://jabs.fums.ac.ir/article-1-1096-en.pdf |
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