An overview of the role of Niemann-pick C1 (NPC1) in viral infections and inhibition of viral infections through NPC1 inhibitor

An overview of the role of Niemann-pick C1 (NPC1) in viral infections and inhibition of viral infections through NPC1 inhibitor

Abstract Viruses communicate with their hosts through interactions with proteins, lipids, and carbohydrate moieties on the plasma membrane (PM), often resulting in viral absorption via receptor-mediated endocytosis. Many viruses cannot multiply unless the host’s cholesterol level remains steady. The...

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Bibliographic Details
Main Authors: Irfan Ahmad, Seyede Narges Fatemi, Mohammad Ghaheri, Ali Rezvani, Dorsa Azizi Khezri, Mohammad Natami, Saman Yasamineh, Omid Gholizadeh, Zahra Bahmanyar
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cell Communication and Signaling
Subjects:
Niemann-pick C1
Viral infection
Ebola virus
SARS-CoV-2
NPC1 inhibitor
Online Access:https://doi.org/10.1186/s12964-023-01376-x

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