Functions of Breast Cancer Predisposition Genes: Implications for Clinical Management

Functions of Breast Cancer Predisposition Genes: Implications for Clinical Management

Approximately 5–10% of all breast cancer (BC) cases are caused by germline pathogenic variants (GPVs) in various cancer predisposition genes (CPGs). The most common contributors to hereditary BC are <i>BRCA1</i> and <i>BRCA2</i>, which are associated with hereditary breast an...

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Bibliographic Details
Main Authors: Akiyo Yoshimura, Issei Imoto, Hiroji Iwata
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
hereditary breast cancer
cancer predisposition gene
function
BRCA
cancer prevention
Online Access:https://www.mdpi.com/1422-0067/23/13/7481

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