A snapshot of the hepatic transcriptome: ad libitum alcohol intake suppresses expression of cholesterol synthesis genes in alcohol-preferring (P) rats.

A snapshot of the hepatic transcriptome: ad libitum alcohol intake suppresses expression of cholesterol synthesis genes in alcohol-preferring (P) rats.

Research is uncovering the genetic and biochemical effects of consuming large quantities of alcohol. One prime example is the J- or U-shaped relationship between the levels of alcohol consumption and the risk of atherosclerotic cardiovascular disease. Moderate alcohol consumption in humans (about 30...

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Bibliographic Details
Main Authors: Jonathon D Klein, Jeremy B Sherrill, Gabriella M Morello, Phillip J San Miguel, Zhenming Ding, Suthat Liangpunsakul, Tiebing Liang, William M Muir, Lawrence Lumeng, Amy C Lossie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4277277?pdf=render

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