Coronary artery aneurysm formation after paclitaxel-coated balloon-only intervention for de novo coronary chronic total occlusion
BackgroundAlthough coronary artery aneurysm (CAA) is an uncommon complication of drug-coated balloon (DCB) treatment, the incidence and mechanisms CAA formation after DCB intervention for chronic total occlusion (CTO) remains to be clarified. The aim of this study was to investigate the incidence of...
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1039316/full |
| _version_ | 1797938317470203904 |
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| author | Eun Jung Jun Eun-Seok Shin Bitna Kim Eu-Vin Teoh Chong-Mow Chu Sunwon Kim Houng Bang Liew |
| author_facet | Eun Jung Jun Eun-Seok Shin Bitna Kim Eu-Vin Teoh Chong-Mow Chu Sunwon Kim Houng Bang Liew |
| author_sort | Eun Jung Jun |
| collection | DOAJ |
| description | BackgroundAlthough coronary artery aneurysm (CAA) is an uncommon complication of drug-coated balloon (DCB) treatment, the incidence and mechanisms CAA formation after DCB intervention for chronic total occlusion (CTO) remains to be clarified. The aim of this study was to investigate the incidence of CAA after DCB intervention for the treatment of CTO of coronary arteries.Materials and methodsThis was a retrospective analysis of 82 patients, contributing 88 vessels, who underwent successful DCB-only treatment for de novo CTO lesions. Follow-up angiography was performed in all cases, at a mean 208.5 (interquartile range [IQR]: 174.8 to 337.5) days after the index procedure.ResultsCAA was identified in seven vessels, in seven patients, at the site of previous successful DCB-only treatment. Of these, six were fusiform in shape and one saccular, with a mean diameter of 4.2 ± 1.0 mm and length of 6.7 ± 2.6 mm. Six CAAs developed at the CTO inlet site, and all CAAs occurred at the lesions following dissection immediately after DCB treatment. CAAs were not associated with an increased risk of major clinical events over the median follow-up of 676.5 (IQR: 393.8 to 1,304.8) days.ConclusionThe incidence of CAA after DCB-only treatment for CTO lesions was 8.0% in this study. Further research is warranted, using intravascular imaging, to clarify the mechanism of DCB-related CAA formation and prognosis. |
| first_indexed | 2024-04-10T18:58:39Z |
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| id | doaj.art-530ebaf03b5f47b197f3ba00bf02754c |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-10T18:58:39Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-530ebaf03b5f47b197f3ba00bf02754c2023-01-31T12:59:15ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-01-01910.3389/fcvm.2022.10393161039316Coronary artery aneurysm formation after paclitaxel-coated balloon-only intervention for de novo coronary chronic total occlusionEun Jung Jun0Eun-Seok Shin1Bitna Kim2Eu-Vin Teoh3Chong-Mow Chu4Sunwon Kim5Houng Bang Liew6Department of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South KoreaDepartment of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South KoreaDepartment of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South KoreaCardiology Department and Clinical Research Center, Queen Elizabeth Hospital II, Kota Kinabalu, MalaysiaCardiology Department and Clinical Research Center, Queen Elizabeth Hospital II, Kota Kinabalu, MalaysiaDepartment of Cardiology, Korea University Ansan Hospital, Ansan-si, South KoreaCardiology Department and Clinical Research Center, Queen Elizabeth Hospital II, Kota Kinabalu, MalaysiaBackgroundAlthough coronary artery aneurysm (CAA) is an uncommon complication of drug-coated balloon (DCB) treatment, the incidence and mechanisms CAA formation after DCB intervention for chronic total occlusion (CTO) remains to be clarified. The aim of this study was to investigate the incidence of CAA after DCB intervention for the treatment of CTO of coronary arteries.Materials and methodsThis was a retrospective analysis of 82 patients, contributing 88 vessels, who underwent successful DCB-only treatment for de novo CTO lesions. Follow-up angiography was performed in all cases, at a mean 208.5 (interquartile range [IQR]: 174.8 to 337.5) days after the index procedure.ResultsCAA was identified in seven vessels, in seven patients, at the site of previous successful DCB-only treatment. Of these, six were fusiform in shape and one saccular, with a mean diameter of 4.2 ± 1.0 mm and length of 6.7 ± 2.6 mm. Six CAAs developed at the CTO inlet site, and all CAAs occurred at the lesions following dissection immediately after DCB treatment. CAAs were not associated with an increased risk of major clinical events over the median follow-up of 676.5 (IQR: 393.8 to 1,304.8) days.ConclusionThe incidence of CAA after DCB-only treatment for CTO lesions was 8.0% in this study. Further research is warranted, using intravascular imaging, to clarify the mechanism of DCB-related CAA formation and prognosis.https://www.frontiersin.org/articles/10.3389/fcvm.2022.1039316/fullcoronary artery aneurysmpaclitaxel-coated balloondrug-coated balloonde novo coronary arterychronic total occlusion |
| spellingShingle | Eun Jung Jun Eun-Seok Shin Bitna Kim Eu-Vin Teoh Chong-Mow Chu Sunwon Kim Houng Bang Liew Coronary artery aneurysm formation after paclitaxel-coated balloon-only intervention for de novo coronary chronic total occlusion Frontiers in Cardiovascular Medicine coronary artery aneurysm paclitaxel-coated balloon drug-coated balloon de novo coronary artery chronic total occlusion |
| title | Coronary artery aneurysm formation after paclitaxel-coated balloon-only intervention for de novo coronary chronic total occlusion |
| title_full | Coronary artery aneurysm formation after paclitaxel-coated balloon-only intervention for de novo coronary chronic total occlusion |
| title_fullStr | Coronary artery aneurysm formation after paclitaxel-coated balloon-only intervention for de novo coronary chronic total occlusion |
| title_full_unstemmed | Coronary artery aneurysm formation after paclitaxel-coated balloon-only intervention for de novo coronary chronic total occlusion |
| title_short | Coronary artery aneurysm formation after paclitaxel-coated balloon-only intervention for de novo coronary chronic total occlusion |
| title_sort | coronary artery aneurysm formation after paclitaxel coated balloon only intervention for de novo coronary chronic total occlusion |
| topic | coronary artery aneurysm paclitaxel-coated balloon drug-coated balloon de novo coronary artery chronic total occlusion |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1039316/full |
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