Challenges encountered with argatroban anticoagulation during cardiopulmonary bypass

Challenges encountered with argatroban anticoagulation during cardiopulmonary bypass

Use of argatroban as an alternative to heparin during cardiopulmonary bypass (CPB) in patients with heparin-induced thrombocytopenia has gained some attention in the past two decades. Dosing of argatroban during CPB is complex due to lack of complete understanding of its pharmacokinetic profile and...

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Bibliographic Details
Main Authors: Shvetank Agarwal, Beth Ullom, Yasser Al-Baghdadi, Michael Okumura
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
Subjects:
Anti-coagulation
argatroban
cardio-pulmonary bypass
heparin induced thrombocytopenia
heparin alternative
Online Access:http://www.joacp.org/article.asp?issn=0970-9185;year=2012;volume=28;issue=1;spage=106;epage=110;aulast=Agarwal

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