Burkitt lymphoma as a cause of intussusceptions: The significance of positron emission tomography scan in the follow-up
Introduction. Burkitt lymphoma (BL) is a high-grade, highrisk type of non-Hodgkin lymphoma characterized by a very rapid cell progression. Although BL is a rare cause of intussusceptions, it must arouse suspicion if the intussusception occurs outside the characteristic peak. Case report. A previous...
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Military Health Department, Ministry of Defance, Serbia
2017-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600182R.pdf |
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| author | Radovanović Zoran Slavković Anđelka Marjanović Zoran Živanović Dragoljub Đorđević Ivona |
| author_facet | Radovanović Zoran Slavković Anđelka Marjanović Zoran Živanović Dragoljub Đorđević Ivona |
| author_sort | Radovanović Zoran |
| collection | DOAJ |
| description | Introduction. Burkitt lymphoma (BL) is a high-grade, highrisk type of non-Hodgkin lymphoma characterized by a very rapid cell progression. Although BL is a rare cause of intussusceptions, it must arouse suspicion if the intussusception occurs outside the characteristic peak. Case report. A previously healthy 7-year-old boy was hospitalized for recurrent abdominal pain, loss of appetite and body weight, a fever of up to 38°C, persistent vomiting and with soft tumefaction ileocecally. Nuclear magnetic resonance (NMR) revealed intussusceptions due to a tumor mass, which was followed by a surgical procedure (right hemicolectomy and terminoterminal anastomosis). Histopathological examination confirmed the diagnosis of primary abdominal Burkitt lymphoma. In spite of the subsequent oncologic treatment lasting for four months, an undifferentiated mass was detected in the retroperitoneal space below the lower pole of the right kidney. Positron emission tomography (PET) scan was performed in order to detect the metabolic activity of the deposit in the retroperitoneal space. A high metabolic activity of Burkitt lymphoma confirmed its presence, as well as the need for additional surgical intervention for tumor extirpation. PET scan undoubtedly contributed to distinguishing the visibility of tumor cells and to the detection of the subcentimeter tumor mass. Conclusion. The timely diagnosis, high tumor sensitivity to chemotherapy as well as the great importance of PET scan in the early detection of tumor recurrence, significantly increase the survival rate in patients with BL. |
| first_indexed | 2024-04-13T23:17:19Z |
| format | Article |
| id | doaj.art-531736936b5c4266b91e73690c062a79 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 2406-0720 |
| language | English |
| last_indexed | 2024-04-13T23:17:19Z |
| publishDate | 2017-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-531736936b5c4266b91e73690c062a792022-12-22T02:25:22ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202017-01-0174329429710.2298/VSP150710182R0042-84501600182RBurkitt lymphoma as a cause of intussusceptions: The significance of positron emission tomography scan in the follow-upRadovanović Zoran0Slavković Anđelka1Marjanović Zoran2Živanović Dragoljub3Đorđević Ivona4Clinical Center Niš, Center for Radiology, Niš + Faculty of Medicine, NišFaculty of Medicine, Niš + Clinical Center Niš, Pediatric Surgery Clinic, NišFaculty of Medicine, Niš + Clinical Center Niš, Pediatric Surgery Clinic, NišFaculty of Medicine, Niš + Clinical Center Niš, Pediatric Surgery Clinic, NišClinical Center Niš, Pediatric Surgery Clinic, NišIntroduction. Burkitt lymphoma (BL) is a high-grade, highrisk type of non-Hodgkin lymphoma characterized by a very rapid cell progression. Although BL is a rare cause of intussusceptions, it must arouse suspicion if the intussusception occurs outside the characteristic peak. Case report. A previously healthy 7-year-old boy was hospitalized for recurrent abdominal pain, loss of appetite and body weight, a fever of up to 38°C, persistent vomiting and with soft tumefaction ileocecally. Nuclear magnetic resonance (NMR) revealed intussusceptions due to a tumor mass, which was followed by a surgical procedure (right hemicolectomy and terminoterminal anastomosis). Histopathological examination confirmed the diagnosis of primary abdominal Burkitt lymphoma. In spite of the subsequent oncologic treatment lasting for four months, an undifferentiated mass was detected in the retroperitoneal space below the lower pole of the right kidney. Positron emission tomography (PET) scan was performed in order to detect the metabolic activity of the deposit in the retroperitoneal space. A high metabolic activity of Burkitt lymphoma confirmed its presence, as well as the need for additional surgical intervention for tumor extirpation. PET scan undoubtedly contributed to distinguishing the visibility of tumor cells and to the detection of the subcentimeter tumor mass. Conclusion. The timely diagnosis, high tumor sensitivity to chemotherapy as well as the great importance of PET scan in the early detection of tumor recurrence, significantly increase the survival rate in patients with BL.http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600182R.pdfBurkitt lymphomadiagnosis, differentialintussusceptionschildpositron-emission tomographydigestive system surgical proceduresantineoplastic combined chemotherapy protocols |
| spellingShingle | Radovanović Zoran Slavković Anđelka Marjanović Zoran Živanović Dragoljub Đorđević Ivona Burkitt lymphoma as a cause of intussusceptions: The significance of positron emission tomography scan in the follow-up Vojnosanitetski Pregled Burkitt lymphoma diagnosis, differential intussusceptions child positron-emission tomography digestive system surgical procedures antineoplastic combined chemotherapy protocols |
| title | Burkitt lymphoma as a cause of intussusceptions: The significance of positron emission tomography scan in the follow-up |
| title_full | Burkitt lymphoma as a cause of intussusceptions: The significance of positron emission tomography scan in the follow-up |
| title_fullStr | Burkitt lymphoma as a cause of intussusceptions: The significance of positron emission tomography scan in the follow-up |
| title_full_unstemmed | Burkitt lymphoma as a cause of intussusceptions: The significance of positron emission tomography scan in the follow-up |
| title_short | Burkitt lymphoma as a cause of intussusceptions: The significance of positron emission tomography scan in the follow-up |
| title_sort | burkitt lymphoma as a cause of intussusceptions the significance of positron emission tomography scan in the follow up |
| topic | Burkitt lymphoma diagnosis, differential intussusceptions child positron-emission tomography digestive system surgical procedures antineoplastic combined chemotherapy protocols |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600182R.pdf |
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