Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2022-09-01
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| Series: | Signal Transduction and Targeted Therapy |
| Online Access: | https://doi.org/10.1038/s41392-022-01128-2 |
| _version_ | 1798002968950210560 |
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| author | Shuaishuai Ni Qian Liu Xin Chen Lele Ding Lili Cai Fei Mao Donglei Shi Robert M. Hoffman Jian Li Lijun Jia |
| author_facet | Shuaishuai Ni Qian Liu Xin Chen Lele Ding Lili Cai Fei Mao Donglei Shi Robert M. Hoffman Jian Li Lijun Jia |
| author_sort | Shuaishuai Ni |
| collection | DOAJ |
| first_indexed | 2024-04-11T12:00:47Z |
| format | Article |
| id | doaj.art-53198fa59feb42b3a13be40d57100d84 |
| institution | Directory Open Access Journal |
| issn | 2059-3635 |
| language | English |
| last_indexed | 2024-04-11T12:00:47Z |
| publishDate | 2022-09-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Signal Transduction and Targeted Therapy |
| spelling | doaj.art-53198fa59feb42b3a13be40d57100d842022-12-22T04:24:51ZengNature Publishing GroupSignal Transduction and Targeted Therapy2059-36352022-09-01711410.1038/s41392-022-01128-2Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cellsShuaishuai Ni0Qian Liu1Xin Chen2Lele Ding3Lili Cai4Fei Mao5Donglei Shi6Robert M. Hoffman7Jian Li8Lijun Jia9Cancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese MedicineCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese MedicineState Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and TechnologyCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese MedicineCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese MedicineState Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and TechnologyState Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and TechnologyDepartment of Surgery, University of CaliforniaState Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and TechnologyCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicinehttps://doi.org/10.1038/s41392-022-01128-2 |
| spellingShingle | Shuaishuai Ni Qian Liu Xin Chen Lele Ding Lili Cai Fei Mao Donglei Shi Robert M. Hoffman Jian Li Lijun Jia Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells Signal Transduction and Targeted Therapy |
| title | Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells |
| title_full | Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells |
| title_fullStr | Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells |
| title_full_unstemmed | Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells |
| title_short | Pro-senescence neddylation inhibitor combined with a senescence activated β-galactosidase prodrug to selectively target cancer cells |
| title_sort | pro senescence neddylation inhibitor combined with a senescence activated β galactosidase prodrug to selectively target cancer cells |
| url | https://doi.org/10.1038/s41392-022-01128-2 |
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