Cell cycle-dependent activation of proneural transcription factor expression and reactive gliosis in rat Müller glia
Abstract Retinal Müller glia have a capacity to regenerate neurons in lower vertebrates like zebrafish, but such ability is extremely limited in mammals. In zebrafish, Müller glia proliferate after injury, which promotes their neurogenic reprogramming while inhibiting reactive gliosis. In mammals, h...
Main Authors: | Reiko Nishino, Kaori Nomura-Komoike, Tomohiro Iida, Hiroki Fujieda |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-50222-0 |
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