Neural precursor cells tune striatal connectivity through the release of IGFBPL1

Neural precursor cells tune striatal connectivity through the release of IGFBPL1

The physiological role of endogenous neural protenitor cells of the subventricular zone in adult stage is not fully understood. Here the authors show that in mice, these cells tune neuronal activity of the striatum via insulin-like growth factor binding protein-like 1 and cognitive functions.

Bibliographic Details
Main Authors: Erica Butti, Stefano Cattaneo, Marco Bacigaluppi, Marco Cambiaghi, Giulia Maria Scotti, Elena Brambilla, Francesca Ruffini, Giacomo Sferruzza, Maddalena Ripamonti, Fabio Simeoni, Laura Cacciaguerra, Aurora Zanghì, Angelo Quattrini, Riccardo Fesce, Paola Panina-Bordignon, Francesca Giannese, Davide Cittaro, Tanja Kuhlmann, Patrizia D’Adamo, Maria Assunta Rocca, Stefano Taverna, Gianvito Martino
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35341-y

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