Microwave-Assisted Dehydrogenative Cross Coupling Reactions in γ-valerolactone with a Reusable Pd/β-cyclodextrin Crosslinked Catalyst
Transition-metal mediated C–H bond activation and functionalization is one of the most straightforward and powerful tools in modern organic synthetic chemistry. Oxidative C–H/C–H coupling reactions between two (hetero)arenes under heterogeneous catalysis may be a valuable means for the production of...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-01-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/24/2/288 |
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| author | Silvia Tabasso Emanuela Calcio Gaudino Elisa Acciardo Maela Manzoli Agnese Giacomino Giancarlo Cravotto |
| author_facet | Silvia Tabasso Emanuela Calcio Gaudino Elisa Acciardo Maela Manzoli Agnese Giacomino Giancarlo Cravotto |
| author_sort | Silvia Tabasso |
| collection | DOAJ |
| description | Transition-metal mediated C–H bond activation and functionalization is one of the most straightforward and powerful tools in modern organic synthetic chemistry. Oxidative C–H/C–H coupling reactions between two (hetero)arenes under heterogeneous catalysis may be a valuable means for the production of a plethora of bi(hetero)aryls, and one that adheres to the increasing demand for atom-economic and sustainable chemistry. We have therefore developed a reusable heterogeneous catalytic system, which is based on Pd cross-linked β-cyclodextrin, to perform an efficient microwave-assisted oxidative C–H/C–H cross coupling process between benzothiazoles and methyl thiophene in the presence of green solvents. |
| first_indexed | 2024-12-16T08:33:03Z |
| format | Article |
| id | doaj.art-5320bf831b23444792568a732e55e8b8 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-16T08:33:03Z |
| publishDate | 2019-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-5320bf831b23444792568a732e55e8b82022-12-21T22:37:50ZengMDPI AGMolecules1420-30492019-01-0124228810.3390/molecules24020288molecules24020288Microwave-Assisted Dehydrogenative Cross Coupling Reactions in γ-valerolactone with a Reusable Pd/β-cyclodextrin Crosslinked CatalystSilvia Tabasso0Emanuela Calcio Gaudino1Elisa Acciardo2Maela Manzoli3Agnese Giacomino4Giancarlo Cravotto5Department of Chemistry, University of Turin, Via P. Giuria 7, 10125 Turin, ItalyDepartment of Drug Science and Technology and NIS - Centre for Nanostructured Interfaces and Surfaces, University of Turin, Via P. Giuria 9, 10125 Turin, ItalyDepartment of Drug Science and Technology and NIS - Centre for Nanostructured Interfaces and Surfaces, University of Turin, Via P. Giuria 9, 10125 Turin, ItalyDepartment of Drug Science and Technology and NIS - Centre for Nanostructured Interfaces and Surfaces, University of Turin, Via P. Giuria 9, 10125 Turin, ItalyDepartment of Drug Science and Technology and NIS - Centre for Nanostructured Interfaces and Surfaces, University of Turin, Via P. Giuria 9, 10125 Turin, ItalyDepartment of Drug Science and Technology and NIS - Centre for Nanostructured Interfaces and Surfaces, University of Turin, Via P. Giuria 9, 10125 Turin, ItalyTransition-metal mediated C–H bond activation and functionalization is one of the most straightforward and powerful tools in modern organic synthetic chemistry. Oxidative C–H/C–H coupling reactions between two (hetero)arenes under heterogeneous catalysis may be a valuable means for the production of a plethora of bi(hetero)aryls, and one that adheres to the increasing demand for atom-economic and sustainable chemistry. We have therefore developed a reusable heterogeneous catalytic system, which is based on Pd cross-linked β-cyclodextrin, to perform an efficient microwave-assisted oxidative C–H/C–H cross coupling process between benzothiazoles and methyl thiophene in the presence of green solvents.http://www.mdpi.com/1420-3049/24/2/288microwavesC–H activationheterogeneous catalystdehydrogenative cross couplingGVL |
| spellingShingle | Silvia Tabasso Emanuela Calcio Gaudino Elisa Acciardo Maela Manzoli Agnese Giacomino Giancarlo Cravotto Microwave-Assisted Dehydrogenative Cross Coupling Reactions in γ-valerolactone with a Reusable Pd/β-cyclodextrin Crosslinked Catalyst Molecules microwaves C–H activation heterogeneous catalyst dehydrogenative cross coupling GVL |
| title | Microwave-Assisted Dehydrogenative Cross Coupling Reactions in γ-valerolactone with a Reusable Pd/β-cyclodextrin Crosslinked Catalyst |
| title_full | Microwave-Assisted Dehydrogenative Cross Coupling Reactions in γ-valerolactone with a Reusable Pd/β-cyclodextrin Crosslinked Catalyst |
| title_fullStr | Microwave-Assisted Dehydrogenative Cross Coupling Reactions in γ-valerolactone with a Reusable Pd/β-cyclodextrin Crosslinked Catalyst |
| title_full_unstemmed | Microwave-Assisted Dehydrogenative Cross Coupling Reactions in γ-valerolactone with a Reusable Pd/β-cyclodextrin Crosslinked Catalyst |
| title_short | Microwave-Assisted Dehydrogenative Cross Coupling Reactions in γ-valerolactone with a Reusable Pd/β-cyclodextrin Crosslinked Catalyst |
| title_sort | microwave assisted dehydrogenative cross coupling reactions in γ valerolactone with a reusable pd β cyclodextrin crosslinked catalyst |
| topic | microwaves C–H activation heterogeneous catalyst dehydrogenative cross coupling GVL |
| url | http://www.mdpi.com/1420-3049/24/2/288 |
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