Impact of Diabetes Mellitus on Cervical Spine Surgery for Ossification of the Posterior Longitudinal Ligament
Ossification of the posterior longitudinal ligament (OPLL) is commonly associated with diabetes mellitus (DM); however, the impact of DM on cervical spine surgery for OPLL remains unclear. This study was performed to evaluate the influence of diabetes DM on the outcomes following cervical spine surg...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-07-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/10/15/3375 |
| _version_ | 1797525441989312512 |
|---|---|
| author | Atsushi Kimura Katsushi Takeshita Toshitaka Yoshii Satoru Egawa Takashi Hirai Kenichiro Sakai Kazuo Kusano Yukihiro Nakagawa Kanichiro Wada Keiichi Katsumi Kengo Fujii Takeo Furuya Narihito Nagoshi Tsukasa Kanchiku Yukitaka Nagamoto Yasushi Oshima Hiroaki Nakashima Kei Ando Masahiko Takahata Kanji Mori Hideaki Nakajima Kazuma Murata Shunji Matsunaga Takashi Kaito Kei Yamada Sho Kobayashi Satoshi Kato Tetsuro Ohba Satoshi Inami Shunsuke Fujibayashi Hiroyuki Katoh Haruo Kanno Kota Watanabe Shiro Imagama Masao Koda Yoshiharu Kawaguchi Masaya Nakamura Morio Matsumoto Masashi Yamazaki Atsushi Okawa |
| author_facet | Atsushi Kimura Katsushi Takeshita Toshitaka Yoshii Satoru Egawa Takashi Hirai Kenichiro Sakai Kazuo Kusano Yukihiro Nakagawa Kanichiro Wada Keiichi Katsumi Kengo Fujii Takeo Furuya Narihito Nagoshi Tsukasa Kanchiku Yukitaka Nagamoto Yasushi Oshima Hiroaki Nakashima Kei Ando Masahiko Takahata Kanji Mori Hideaki Nakajima Kazuma Murata Shunji Matsunaga Takashi Kaito Kei Yamada Sho Kobayashi Satoshi Kato Tetsuro Ohba Satoshi Inami Shunsuke Fujibayashi Hiroyuki Katoh Haruo Kanno Kota Watanabe Shiro Imagama Masao Koda Yoshiharu Kawaguchi Masaya Nakamura Morio Matsumoto Masashi Yamazaki Atsushi Okawa |
| author_sort | Atsushi Kimura |
| collection | DOAJ |
| description | Ossification of the posterior longitudinal ligament (OPLL) is commonly associated with diabetes mellitus (DM); however, the impact of DM on cervical spine surgery for OPLL remains unclear. This study was performed to evaluate the influence of diabetes DM on the outcomes following cervical spine surgery for OPLL. In total, 478 patients with cervical OPLL who underwent surgical treatment were prospectively recruited from April 2015 to July 2017. Functional measurements were conducted at baseline and at 6 months, 1 year, and 2 years after surgery using JOA and JOACMEQ scores. The incidence of postoperative complications was categorized into early (≤30 days) and late (>30 days), depending on the time from surgery. From the initial group of 478 patients, 402 completed the 2-year follow-up and were included in the analysis. Of the 402 patients, 127 (32%) had DM as a comorbid disease. The overall incidence of postoperative complications was significantly higher in patients with DM than in patients without DM in both the early and late postoperative periods. The patients with DM had a significantly lower JOA score and JOACMEQ scores in the domains of lower extremity function and quality of life than those without DM at the 2-year follow-up. |
| first_indexed | 2024-03-10T09:12:54Z |
| format | Article |
| id | doaj.art-53228c315e8e4cedaee467dfe4b5d345 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T09:12:54Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-53228c315e8e4cedaee467dfe4b5d3452023-11-22T05:49:51ZengMDPI AGJournal of Clinical Medicine2077-03832021-07-011015337510.3390/jcm10153375Impact of Diabetes Mellitus on Cervical Spine Surgery for Ossification of the Posterior Longitudinal LigamentAtsushi Kimura0Katsushi Takeshita1Toshitaka Yoshii2Satoru Egawa3Takashi Hirai4Kenichiro Sakai5Kazuo Kusano6Yukihiro Nakagawa7Kanichiro Wada8Keiichi Katsumi9Kengo Fujii10Takeo Furuya11Narihito Nagoshi12Tsukasa Kanchiku13Yukitaka Nagamoto14Yasushi Oshima15Hiroaki Nakashima16Kei Ando17Masahiko Takahata18Kanji Mori19Hideaki Nakajima20Kazuma Murata21Shunji Matsunaga22Takashi Kaito23Kei Yamada24Sho Kobayashi25Satoshi Kato26Tetsuro Ohba27Satoshi Inami28Shunsuke Fujibayashi29Hiroyuki Katoh30Haruo Kanno31Kota Watanabe32Shiro Imagama33Masao Koda34Yoshiharu Kawaguchi35Masaya Nakamura36Morio Matsumoto37Masashi Yamazaki38Atsushi Okawa39Department of Orthopedics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke 329-0498, Tochigi, JapanDepartment of Orthopedics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke 329-0498, Tochigi, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanDepartment of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku Ward, Tokyo 160-8582, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanJapanese Multicenter Research Organization for Ossification of the Spinal Ligament, Tokyo 113-8510, JapanOssification of the posterior longitudinal ligament (OPLL) is commonly associated with diabetes mellitus (DM); however, the impact of DM on cervical spine surgery for OPLL remains unclear. This study was performed to evaluate the influence of diabetes DM on the outcomes following cervical spine surgery for OPLL. In total, 478 patients with cervical OPLL who underwent surgical treatment were prospectively recruited from April 2015 to July 2017. Functional measurements were conducted at baseline and at 6 months, 1 year, and 2 years after surgery using JOA and JOACMEQ scores. The incidence of postoperative complications was categorized into early (≤30 days) and late (>30 days), depending on the time from surgery. From the initial group of 478 patients, 402 completed the 2-year follow-up and were included in the analysis. Of the 402 patients, 127 (32%) had DM as a comorbid disease. The overall incidence of postoperative complications was significantly higher in patients with DM than in patients without DM in both the early and late postoperative periods. The patients with DM had a significantly lower JOA score and JOACMEQ scores in the domains of lower extremity function and quality of life than those without DM at the 2-year follow-up.https://www.mdpi.com/2077-0383/10/15/3375ossification of the posterior longitudinal ligamentcervical myelopathydiabetes mellitussurgical outcome |
| spellingShingle | Atsushi Kimura Katsushi Takeshita Toshitaka Yoshii Satoru Egawa Takashi Hirai Kenichiro Sakai Kazuo Kusano Yukihiro Nakagawa Kanichiro Wada Keiichi Katsumi Kengo Fujii Takeo Furuya Narihito Nagoshi Tsukasa Kanchiku Yukitaka Nagamoto Yasushi Oshima Hiroaki Nakashima Kei Ando Masahiko Takahata Kanji Mori Hideaki Nakajima Kazuma Murata Shunji Matsunaga Takashi Kaito Kei Yamada Sho Kobayashi Satoshi Kato Tetsuro Ohba Satoshi Inami Shunsuke Fujibayashi Hiroyuki Katoh Haruo Kanno Kota Watanabe Shiro Imagama Masao Koda Yoshiharu Kawaguchi Masaya Nakamura Morio Matsumoto Masashi Yamazaki Atsushi Okawa Impact of Diabetes Mellitus on Cervical Spine Surgery for Ossification of the Posterior Longitudinal Ligament Journal of Clinical Medicine ossification of the posterior longitudinal ligament cervical myelopathy diabetes mellitus surgical outcome |
| title | Impact of Diabetes Mellitus on Cervical Spine Surgery for Ossification of the Posterior Longitudinal Ligament |
| title_full | Impact of Diabetes Mellitus on Cervical Spine Surgery for Ossification of the Posterior Longitudinal Ligament |
| title_fullStr | Impact of Diabetes Mellitus on Cervical Spine Surgery for Ossification of the Posterior Longitudinal Ligament |
| title_full_unstemmed | Impact of Diabetes Mellitus on Cervical Spine Surgery for Ossification of the Posterior Longitudinal Ligament |
| title_short | Impact of Diabetes Mellitus on Cervical Spine Surgery for Ossification of the Posterior Longitudinal Ligament |
| title_sort | impact of diabetes mellitus on cervical spine surgery for ossification of the posterior longitudinal ligament |
| topic | ossification of the posterior longitudinal ligament cervical myelopathy diabetes mellitus surgical outcome |
| url | https://www.mdpi.com/2077-0383/10/15/3375 |
| work_keys_str_mv | AT atsushikimura impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT katsushitakeshita impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT toshitakayoshii impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT satoruegawa impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT takashihirai impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT kenichirosakai impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT kazuokusano impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT yukihironakagawa impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT kanichirowada impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT keiichikatsumi impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT kengofujii impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT takeofuruya impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT narihitonagoshi impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT tsukasakanchiku impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT yukitakanagamoto impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT yasushioshima impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT hiroakinakashima impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT keiando impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT masahikotakahata impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT kanjimori impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT hideakinakajima impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT kazumamurata impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT shunjimatsunaga impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT takashikaito impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT keiyamada impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT shokobayashi impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT satoshikato impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT tetsuroohba impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT satoshiinami impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT shunsukefujibayashi impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT hiroyukikatoh impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT haruokanno impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT kotawatanabe impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT shiroimagama impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT masaokoda impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT yoshiharukawaguchi impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT masayanakamura impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT moriomatsumoto impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT masashiyamazaki impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament AT atsushiokawa impactofdiabetesmellitusoncervicalspinesurgeryforossificationoftheposteriorlongitudinalligament |