Liposomic nano particles in the treatment of colorectal and ovarian cancer
Cancer is an expansionist disease, it invades through tissues, sets up colonies in hostile landscapes, seeking “sanctuary” in one organ and then immigrating to another. Ovarian and colorectal cancer has high mortality rates in India. Colorectal cancer typically begins in the gut lining and can sprea...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-08-01
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| Series: | European Journal of Medicinal Chemistry Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417424000219 |
| _version_ | 1797253835770560512 |
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| author | Sheikh Rezzak Ali Chinmoyee Deori Gaurab Kr Gogoi Naba Jyoti Borah Prajnyan Prasad Kalita Rubina Chowdhury Simran Kaur Bibhuti Bhusan Kakoti |
| author_facet | Sheikh Rezzak Ali Chinmoyee Deori Gaurab Kr Gogoi Naba Jyoti Borah Prajnyan Prasad Kalita Rubina Chowdhury Simran Kaur Bibhuti Bhusan Kakoti |
| author_sort | Sheikh Rezzak Ali |
| collection | DOAJ |
| description | Cancer is an expansionist disease, it invades through tissues, sets up colonies in hostile landscapes, seeking “sanctuary” in one organ and then immigrating to another. Ovarian and colorectal cancer has high mortality rates in India. Colorectal cancer typically begins in the gut lining and can spread through the colon wall and beneath the muscular layers, and is a significant source of morbidity. Ovarian cancer has the highest recurrence rate of all gynaecologic cancers and has high mortality because of late diagnosis brought on by vague symptoms. In this review article, we have discussed that apart from the conventional ways of treatment, how nanoparticles has the potential to improve the detection, diagnosis, and treatment of these cancers. Liposomal nanoparticles are lipid-based vesicles that can encapsulate drugs and deliver them to specific targets in the body, potentially improving the effectiveness and reducing the side effects of the treatment. This article also provides an insight on the fact that while liposomal nanoparticles show promising effect, there are challenges to be addressed, including optimizing drug release rates, and ensuring effective targeting. |
| first_indexed | 2024-04-24T21:40:23Z |
| format | Article |
| id | doaj.art-53245ecc7f9f47c88fb2070943853102 |
| institution | Directory Open Access Journal |
| issn | 2772-4174 |
| language | English |
| last_indexed | 2024-04-24T21:40:23Z |
| publishDate | 2024-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | European Journal of Medicinal Chemistry Reports |
| spelling | doaj.art-53245ecc7f9f47c88fb20709438531022024-03-21T05:38:27ZengElsevierEuropean Journal of Medicinal Chemistry Reports2772-41742024-08-0111100149Liposomic nano particles in the treatment of colorectal and ovarian cancerSheikh Rezzak Ali0Chinmoyee Deori1Gaurab Kr Gogoi2Naba Jyoti Borah3Prajnyan Prasad Kalita4Rubina Chowdhury5Simran Kaur6Bibhuti Bhusan Kakoti7Department of Pharmaceutical Sciences, School of Science and Engineering, Dibrugarh University, Dibrugarh, 786004, Assam, India; Corresponding author. Department of Pharmaceutical Sciences, School of Science and Engineering, Dibrugarh University, Dibrugarh, 786004, Assam, India.Lakhimpur Medical College and Hospital, Chowkham, 787051, Assam, IndiaLakhimpur Medical College and Hospital, Chowkham, 787051, Assam, IndiaLakhimpur Medical College and Hospital, Chowkham, 787051, Assam, IndiaLakhimpur Medical College and Hospital, Chowkham, 787051, Assam, IndiaSchool of Pharmaceutical Sciences, Girijananda Chowdhury University-Tezpur Campus, Sonitpur, Assam, 784501, IndiaCentre for Biotechnology and Bioinformatics, Dibrugarh University, Dibrugarh, 786004, Assam, IndiaDepartment of Pharmaceutical Sciences, School of Science and Engineering, Dibrugarh University, Dibrugarh, 786004, Assam, IndiaCancer is an expansionist disease, it invades through tissues, sets up colonies in hostile landscapes, seeking “sanctuary” in one organ and then immigrating to another. Ovarian and colorectal cancer has high mortality rates in India. Colorectal cancer typically begins in the gut lining and can spread through the colon wall and beneath the muscular layers, and is a significant source of morbidity. Ovarian cancer has the highest recurrence rate of all gynaecologic cancers and has high mortality because of late diagnosis brought on by vague symptoms. In this review article, we have discussed that apart from the conventional ways of treatment, how nanoparticles has the potential to improve the detection, diagnosis, and treatment of these cancers. Liposomal nanoparticles are lipid-based vesicles that can encapsulate drugs and deliver them to specific targets in the body, potentially improving the effectiveness and reducing the side effects of the treatment. This article also provides an insight on the fact that while liposomal nanoparticles show promising effect, there are challenges to be addressed, including optimizing drug release rates, and ensuring effective targeting.http://www.sciencedirect.com/science/article/pii/S2772417424000219LiposomesNanoparticlesColorectal cancerOvarian cancer |
| spellingShingle | Sheikh Rezzak Ali Chinmoyee Deori Gaurab Kr Gogoi Naba Jyoti Borah Prajnyan Prasad Kalita Rubina Chowdhury Simran Kaur Bibhuti Bhusan Kakoti Liposomic nano particles in the treatment of colorectal and ovarian cancer European Journal of Medicinal Chemistry Reports Liposomes Nanoparticles Colorectal cancer Ovarian cancer |
| title | Liposomic nano particles in the treatment of colorectal and ovarian cancer |
| title_full | Liposomic nano particles in the treatment of colorectal and ovarian cancer |
| title_fullStr | Liposomic nano particles in the treatment of colorectal and ovarian cancer |
| title_full_unstemmed | Liposomic nano particles in the treatment of colorectal and ovarian cancer |
| title_short | Liposomic nano particles in the treatment of colorectal and ovarian cancer |
| title_sort | liposomic nano particles in the treatment of colorectal and ovarian cancer |
| topic | Liposomes Nanoparticles Colorectal cancer Ovarian cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2772417424000219 |
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