Thyroid Hormone Enhances Angiogenesis and the Warburg Effect in Squamous Cell Carcinomas

Thyroid Hormone Enhances Angiogenesis and the Warburg Effect in Squamous Cell Carcinomas

Cancer angiogenesis is required to support energetic demand and metabolic stress, particularly during conditions of hypoxia. Coupled to neo-vasculogenesis, cancer cells rewire metabolic programs to sustain growth, survival and long-term maintenance. Thyroid hormone (TH) signaling regulates growth an...

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Bibliographic Details
Main Authors: Caterina Miro, Annarita Nappi, Annunziata Gaetana Cicatiello, Emery Di Cicco, Serena Sagliocchi, Melania Murolo, Valentina Belli, Teresa Troiani, Sandra Albanese, Sara Amiranda, Ann Marie Zavacki, Mariano Stornaiuolo, Marcello Mancini, Domenico Salvatore, Monica Dentice
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
thyroid hormones
deiodinases
angiogenesis
squamous cell carcinoma
Online Access:https://www.mdpi.com/2072-6694/13/11/2743

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