Monte-Carlo Simulation of Light Tissue Interaction in Medical Hyperspectral Imaging Applications

In Hyperspectral imaging (HSI) applications in medicine a uniform illumination is used and the illuminated surface is recorded with a camera with spectral resolution. Unlike in tissue reflectance spectroscopy with fixed light source - detector distances, in HSI the contribution of the influence of d...

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Main Authors: Herrmann Bert. H., Hornberger Christoph
Format: Article
Language:English
Published: De Gruyter 2018-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2018-0067
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author Herrmann Bert. H.
Hornberger Christoph
author_facet Herrmann Bert. H.
Hornberger Christoph
author_sort Herrmann Bert. H.
collection DOAJ
description In Hyperspectral imaging (HSI) applications in medicine a uniform illumination is used and the illuminated surface is recorded with a camera with spectral resolution. Unlike in tissue reflectance spectroscopy with fixed light source - detector distances, in HSI the contribution of the influence of different tissue layers to the absorption signal is poorly understood. In this work a Monte-Carlo simulation is implemented which simulates the specific HSI illumination and detector geometry. A four-layer tissue model with variable blood volume fraction and oxygen saturation is used. With 5 % blood volume fraction and 75 % oxygen saturation, SaO2, of surrounding tissue, saturation changes in 1 mm and 2 mm deep layers lead to a change in remission of up to 3 % and up to 1 % respectively. Changes in deeper layers are hardly detectable. Further simulations will be focused on different tissue models as the depth resolution is expected to vary with tissue parameters like blood volume fraction.
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spelling doaj.art-5326103bcc9a4db288da55f4ef70beff2022-12-22T02:43:50ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042018-09-014127527810.1515/cdbme-2018-0067cdbme-2018-0067Monte-Carlo Simulation of Light Tissue Interaction in Medical Hyperspectral Imaging ApplicationsHerrmann Bert. H.0Hornberger Christoph1Hochschule Wismar University of Applied Science Technology, Business and Design Fakultät für Ingenieurwissenschaften Bereich Maschinenbau / Verfahrens und Umwelttechnik, Philipp-Müller- Str. 14, 23966Wismar, GermanyHochschule Wismar University of Applied Science Technology, Business and Design Fakultät für Ingenieurwissenschaften Bereich Maschinenbau / Verfahrens und Umwelttechnik, Philipp-Müller-Str. 14, 23966Wismar, GermanyIn Hyperspectral imaging (HSI) applications in medicine a uniform illumination is used and the illuminated surface is recorded with a camera with spectral resolution. Unlike in tissue reflectance spectroscopy with fixed light source - detector distances, in HSI the contribution of the influence of different tissue layers to the absorption signal is poorly understood. In this work a Monte-Carlo simulation is implemented which simulates the specific HSI illumination and detector geometry. A four-layer tissue model with variable blood volume fraction and oxygen saturation is used. With 5 % blood volume fraction and 75 % oxygen saturation, SaO2, of surrounding tissue, saturation changes in 1 mm and 2 mm deep layers lead to a change in remission of up to 3 % and up to 1 % respectively. Changes in deeper layers are hardly detectable. Further simulations will be focused on different tissue models as the depth resolution is expected to vary with tissue parameters like blood volume fraction.https://doi.org/10.1515/cdbme-2018-0067hyper spectral imagingmonte-carlo simulationoxygenationphantomremission
spellingShingle Herrmann Bert. H.
Hornberger Christoph
Monte-Carlo Simulation of Light Tissue Interaction in Medical Hyperspectral Imaging Applications
Current Directions in Biomedical Engineering
hyper spectral imaging
monte-carlo simulation
oxygenation
phantom
remission
title Monte-Carlo Simulation of Light Tissue Interaction in Medical Hyperspectral Imaging Applications
title_full Monte-Carlo Simulation of Light Tissue Interaction in Medical Hyperspectral Imaging Applications
title_fullStr Monte-Carlo Simulation of Light Tissue Interaction in Medical Hyperspectral Imaging Applications
title_full_unstemmed Monte-Carlo Simulation of Light Tissue Interaction in Medical Hyperspectral Imaging Applications
title_short Monte-Carlo Simulation of Light Tissue Interaction in Medical Hyperspectral Imaging Applications
title_sort monte carlo simulation of light tissue interaction in medical hyperspectral imaging applications
topic hyper spectral imaging
monte-carlo simulation
oxygenation
phantom
remission
url https://doi.org/10.1515/cdbme-2018-0067
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AT hornbergerchristoph montecarlosimulationoflighttissueinteractioninmedicalhyperspectralimagingapplications