A Case of Janumet Poisoning

Janumet, an anti-diabetic drug is being increasingly used. Each tablet contains 50 mg of sitagliptin + 500/1000 mg of metformin. Metformin works by decreasing glucose production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insul...

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Main Authors: Arun Bahulikar, Vihita Kulkarni, Deepak Phalgune
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-11-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/10829/30291_CE(RA1)_F(T)_PF1(PB_AP)_PFA(MJ_SS).pdf
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author Arun Bahulikar
Vihita Kulkarni
Deepak Phalgune
author_facet Arun Bahulikar
Vihita Kulkarni
Deepak Phalgune
author_sort Arun Bahulikar
collection DOAJ
description Janumet, an anti-diabetic drug is being increasingly used. Each tablet contains 50 mg of sitagliptin + 500/1000 mg of metformin. Metformin works by decreasing glucose production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin the body produces after eating (sugar dependant insulin release). A previously healthy 17- year-old female was found to be unconscious and had an alleged history of consumption of eight to nine tablets of Janumet. Patient had seizures on admission and evidence of hypoglycaemia. Patient remained drowsy for two days. Gradually her clinical condition improved and she was diagnosed with an adjustment disorder with disturbance of emotion and conduct. She was discharged from the hospital on the seventh day with normal clinical parameters.
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spelling doaj.art-5326df168f6e47f5b8fc03d997e523dc2022-12-22T02:29:52ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-11-011111OD01OD0210.7860/JCDR/2017/30291.10829A Case of Janumet PoisoningArun Bahulikar0Vihita Kulkarni1Deepak Phalgune2Consultant, Department of Medicine, Poona Hospital and Research Centre, Pune, Maharashtra, India.Consultant, Department of Medicine, Poona Hospital and Research Centre, Pune, Maharashtra, India.Consultant, Department of Research, Poona Hospital and Research Centre, Pune, Maharashtra, India.Janumet, an anti-diabetic drug is being increasingly used. Each tablet contains 50 mg of sitagliptin + 500/1000 mg of metformin. Metformin works by decreasing glucose production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin the body produces after eating (sugar dependant insulin release). A previously healthy 17- year-old female was found to be unconscious and had an alleged history of consumption of eight to nine tablets of Janumet. Patient had seizures on admission and evidence of hypoglycaemia. Patient remained drowsy for two days. Gradually her clinical condition improved and she was diagnosed with an adjustment disorder with disturbance of emotion and conduct. She was discharged from the hospital on the seventh day with normal clinical parameters.https://jcdr.net/articles/PDF/10829/30291_CE(RA1)_F(T)_PF1(PB_AP)_PFA(MJ_SS).pdfhypoglycaemiametforminsitagliptin
spellingShingle Arun Bahulikar
Vihita Kulkarni
Deepak Phalgune
A Case of Janumet Poisoning
Journal of Clinical and Diagnostic Research
hypoglycaemia
metformin
sitagliptin
title A Case of Janumet Poisoning
title_full A Case of Janumet Poisoning
title_fullStr A Case of Janumet Poisoning
title_full_unstemmed A Case of Janumet Poisoning
title_short A Case of Janumet Poisoning
title_sort case of janumet poisoning
topic hypoglycaemia
metformin
sitagliptin
url https://jcdr.net/articles/PDF/10829/30291_CE(RA1)_F(T)_PF1(PB_AP)_PFA(MJ_SS).pdf
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