From drug-delivery device to disease management tool: a study of preferences for enhanced features in next-generation self-injection devices
Marco Boeri,1 Boglarka Szegvari,2 Brett Hauber,3 Brennan Mange,3 Irina Mountian,2 Michael Schiff,4 Nikolaos Maniadakis51RTI Health Solutions, Belfast, UK; 2UCB Pharma, Brussels, Belgium; 3RTI Health Solutions, Research Triangle Park, NC, USA; 4Rheumatology Division, University of Colorado School of...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-07-01
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| Series: | Patient Preference and Adherence |
| Subjects: | |
| Online Access: | https://www.dovepress.com/from-drug-delivery-device-to-disease-management-tool-a-study-of-prefer-peer-reviewed-article-PPA |
| _version_ | 1818969934235959296 |
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| author | Boeri M Szegvari B Hauber B Mange B Mountian I Schiff M Maniadakis N |
| author_facet | Boeri M Szegvari B Hauber B Mange B Mountian I Schiff M Maniadakis N |
| author_sort | Boeri M |
| collection | DOAJ |
| description | Marco Boeri,1 Boglarka Szegvari,2 Brett Hauber,3 Brennan Mange,3 Irina Mountian,2 Michael Schiff,4 Nikolaos Maniadakis51RTI Health Solutions, Belfast, UK; 2UCB Pharma, Brussels, Belgium; 3RTI Health Solutions, Research Triangle Park, NC, USA; 4Rheumatology Division, University of Colorado School of Medicine, Denver, CO, USA; 5Health Services Management, National School of Public Health, Athens, GreecePurpose: To quantify rheumatology patient preferences and willingness to pay (WTP) for features differentiating enhanced from standard self-injection devices and to investigate differences among subgroups.Patients and methods: Patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA) were recruited in the UK. A discrete-choice experiment was used to elicit preferences; respondents were presented with 10 choices between 3 different devices: a free standard disposable device, and 2 hypothetical reusable devices characterized by presence/absence of skin sensor, injection speed control, on-screen instructions, injection reminders, electronic log, and large grip. Every hypothetical device included a cost component to assess WTP for each enhanced feature. A random-parameters logit model was used to estimate preference weights and WTP.Results: Data were collected from 323 respondents by electronic survey (15/11/2017–15/02/2018; RA: 108; PsA: 103; axSpA: 112). On average, the skin sensor was the most preferred feature (£30), followed by injection speed control, injection reminders, electronic log (∼£20 each), on-screen instructions (∼£12), and a device with a small, rather than large grip (∼£7). Similar preferences for attributes were observed across condition subgroups except for grip size: axSpA patients preferred small grip (∼£27); PsA patients preferred large grip (∼£19). Overall, respondents preferred reusable devices with all enhanced features (WTP value: £85) over the standard device. RA patients exhibited a higher WTP (£145) than PsA (£102) or axSpA (£62) for the same enhanced device.Conclusion: Patients positively valued reusable self-injection devices with enhanced features, which may improve patient experience, potentially improving treatment adherence, clinical, and economic outcomes.Keywords: rheumatology, subcutaneous injection, self-administration, patient preference, discrete-choice experiment |
| first_indexed | 2024-12-20T14:28:28Z |
| format | Article |
| id | doaj.art-5329dbb8755d4f7aa64107903fa0c472 |
| institution | Directory Open Access Journal |
| issn | 1177-889X |
| language | English |
| last_indexed | 2024-12-20T14:28:28Z |
| publishDate | 2019-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Patient Preference and Adherence |
| spelling | doaj.art-5329dbb8755d4f7aa64107903fa0c4722022-12-21T19:37:42ZengDove Medical PressPatient Preference and Adherence1177-889X2019-07-01Volume 131093111047059From drug-delivery device to disease management tool: a study of preferences for enhanced features in next-generation self-injection devicesBoeri MSzegvari BHauber BMange BMountian ISchiff MManiadakis NMarco Boeri,1 Boglarka Szegvari,2 Brett Hauber,3 Brennan Mange,3 Irina Mountian,2 Michael Schiff,4 Nikolaos Maniadakis51RTI Health Solutions, Belfast, UK; 2UCB Pharma, Brussels, Belgium; 3RTI Health Solutions, Research Triangle Park, NC, USA; 4Rheumatology Division, University of Colorado School of Medicine, Denver, CO, USA; 5Health Services Management, National School of Public Health, Athens, GreecePurpose: To quantify rheumatology patient preferences and willingness to pay (WTP) for features differentiating enhanced from standard self-injection devices and to investigate differences among subgroups.Patients and methods: Patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA) were recruited in the UK. A discrete-choice experiment was used to elicit preferences; respondents were presented with 10 choices between 3 different devices: a free standard disposable device, and 2 hypothetical reusable devices characterized by presence/absence of skin sensor, injection speed control, on-screen instructions, injection reminders, electronic log, and large grip. Every hypothetical device included a cost component to assess WTP for each enhanced feature. A random-parameters logit model was used to estimate preference weights and WTP.Results: Data were collected from 323 respondents by electronic survey (15/11/2017–15/02/2018; RA: 108; PsA: 103; axSpA: 112). On average, the skin sensor was the most preferred feature (£30), followed by injection speed control, injection reminders, electronic log (∼£20 each), on-screen instructions (∼£12), and a device with a small, rather than large grip (∼£7). Similar preferences for attributes were observed across condition subgroups except for grip size: axSpA patients preferred small grip (∼£27); PsA patients preferred large grip (∼£19). Overall, respondents preferred reusable devices with all enhanced features (WTP value: £85) over the standard device. RA patients exhibited a higher WTP (£145) than PsA (£102) or axSpA (£62) for the same enhanced device.Conclusion: Patients positively valued reusable self-injection devices with enhanced features, which may improve patient experience, potentially improving treatment adherence, clinical, and economic outcomes.Keywords: rheumatology, subcutaneous injection, self-administration, patient preference, discrete-choice experimenthttps://www.dovepress.com/from-drug-delivery-device-to-disease-management-tool-a-study-of-prefer-peer-reviewed-article-PPARheumatologysubcutaneous injectionself-administrationpatient preferencediscrete-choice experiment |
| spellingShingle | Boeri M Szegvari B Hauber B Mange B Mountian I Schiff M Maniadakis N From drug-delivery device to disease management tool: a study of preferences for enhanced features in next-generation self-injection devices Patient Preference and Adherence Rheumatology subcutaneous injection self-administration patient preference discrete-choice experiment |
| title | From drug-delivery device to disease management tool: a study of preferences for enhanced features in next-generation self-injection devices |
| title_full | From drug-delivery device to disease management tool: a study of preferences for enhanced features in next-generation self-injection devices |
| title_fullStr | From drug-delivery device to disease management tool: a study of preferences for enhanced features in next-generation self-injection devices |
| title_full_unstemmed | From drug-delivery device to disease management tool: a study of preferences for enhanced features in next-generation self-injection devices |
| title_short | From drug-delivery device to disease management tool: a study of preferences for enhanced features in next-generation self-injection devices |
| title_sort | from drug delivery device to disease management tool a study of preferences for enhanced features in next generation self injection devices |
| topic | Rheumatology subcutaneous injection self-administration patient preference discrete-choice experiment |
| url | https://www.dovepress.com/from-drug-delivery-device-to-disease-management-tool-a-study-of-prefer-peer-reviewed-article-PPA |
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