Tissue-specific transformation model for CT-images

During radiotherapy, posture changes and volume changing deformations like growing or shrinking tissue result in anatomical deformations. The basis for investigating the impact of such deformations on dose uncertainties, are model-based tools for deformation analysis. In this context, we propose a t...

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Bibliographic Details
Main Authors: Bartelheimer Kathrin, Teske Hendrik, Bendl Rolf, Giske Kristina
Format: Article
Language:English
Published: De Gruyter 2017-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2017-0111
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author Bartelheimer Kathrin
Teske Hendrik
Bendl Rolf
Giske Kristina
author_facet Bartelheimer Kathrin
Teske Hendrik
Bendl Rolf
Giske Kristina
author_sort Bartelheimer Kathrin
collection DOAJ
description During radiotherapy, posture changes and volume changing deformations like growing or shrinking tissue result in anatomical deformations. The basis for investigating the impact of such deformations on dose uncertainties, are model-based tools for deformation analysis. In this context, we propose a transformation model based on the information of CT-images, which allows an on-the-fly calculation of voxel volumes. Our model is based on the concept of the chainmail algorithm and describes deformation on voxel-level. With an exemplary input of a set of landmark pairs, generated by a kinematic head-and-neck skeleton model, CT-images (512x512x126 voxel) can be deformed with an on-the-fly volume calculation in less than 70s. The volume calculation delivers insight into model-characteristic volume changes and is a prerequisite for implementing tissue growth and shrinkage.
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spelling doaj.art-532af19cd8ff4b8ba7e4e76a7ad155002023-04-11T17:07:14ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042017-09-013252552810.1515/cdbme-2017-0111cdbme-2017-0111Tissue-specific transformation model for CT-imagesBartelheimer Kathrin0Teske Hendrik1Bendl Rolf2Giske Kristina3Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ) Heidelberg, National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Im Neuenheimer Feld 280, 69120 Heidelberg, GermanyDivision of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ) Heidelberg, National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Germany Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ) Heidelberg, Heilbronn University, Faculty of Computer Science, Germany Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ) Heidelberg, National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Germany During radiotherapy, posture changes and volume changing deformations like growing or shrinking tissue result in anatomical deformations. The basis for investigating the impact of such deformations on dose uncertainties, are model-based tools for deformation analysis. In this context, we propose a transformation model based on the information of CT-images, which allows an on-the-fly calculation of voxel volumes. Our model is based on the concept of the chainmail algorithm and describes deformation on voxel-level. With an exemplary input of a set of landmark pairs, generated by a kinematic head-and-neck skeleton model, CT-images (512x512x126 voxel) can be deformed with an on-the-fly volume calculation in less than 70s. The volume calculation delivers insight into model-characteristic volume changes and is a prerequisite for implementing tissue growth and shrinkage.https://doi.org/10.1515/cdbme-2017-0111soft tissue deformationvolume changing deformationstransformation modechainmail algorithm
spellingShingle Bartelheimer Kathrin
Teske Hendrik
Bendl Rolf
Giske Kristina
Tissue-specific transformation model for CT-images
Current Directions in Biomedical Engineering
soft tissue deformation
volume changing deformations
transformation mode
chainmail algorithm
title Tissue-specific transformation model for CT-images
title_full Tissue-specific transformation model for CT-images
title_fullStr Tissue-specific transformation model for CT-images
title_full_unstemmed Tissue-specific transformation model for CT-images
title_short Tissue-specific transformation model for CT-images
title_sort tissue specific transformation model for ct images
topic soft tissue deformation
volume changing deformations
transformation mode
chainmail algorithm
url https://doi.org/10.1515/cdbme-2017-0111
work_keys_str_mv AT bartelheimerkathrin tissuespecifictransformationmodelforctimages
AT teskehendrik tissuespecifictransformationmodelforctimages
AT bendlrolf tissuespecifictransformationmodelforctimages
AT giskekristina tissuespecifictransformationmodelforctimages