Electron-microscopic features of changes in the adrenal and thyroid glands in chronic hypoxia

The aim of the study was to study the characteristic features of ultrastructural changes in the cellular and extracellular matrix of the adrenal and thyroid glands in chronic hypoxia.Materials and methods. The study used the thyroid and adrenal glands of healthy adult male white rats weighing 180-20...

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Main Author: S. M. Yagubova
Format: Article
Language:Russian
Published: Private institution educational organization of higher education "Medical University "ReaViz" 2021-10-01
Series:Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
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Online Access:https://vestnik.reaviz.ru/jour/article/view/318
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author S. M. Yagubova
author_facet S. M. Yagubova
author_sort S. M. Yagubova
collection DOAJ
description The aim of the study was to study the characteristic features of ultrastructural changes in the cellular and extracellular matrix of the adrenal and thyroid glands in chronic hypoxia.Materials and methods. The study used the thyroid and adrenal glands of healthy adult male white rats weighing 180-200 g. The anatomical, histological, histochemical, electron microscopic and morphometric methods were used.Results. We found that the response of thyroid and adrenal cells to hypoxia is different. So, since the processes of proliferation in the cells of the thyroid gland occur faster and earlier, all tissues are restored on the 15th day of the experiment in the thyroid gland, and in the adrenal gland are restored only on the 30th day of the experiment. And this can be regarded as a higher degree of sensitivity of the adrenal glands to hypoxia, which is a stronger stress factor than the thyroid gland.Summary. The structures of the thyroid gland adapt to long-term hypoxia earlier, and responds to this with ultrastructural rearrangement – hyperplasia, hypertrophy and proliferation of thyrocytes.
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series Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
spelling doaj.art-532efb925cc7484e9f7891a5bcfdb21a2025-03-02T09:38:10ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792021-10-01115425010.20340/vmi-rvz.2021.5.MORPH.1258Electron-microscopic features of changes in the adrenal and thyroid glands in chronic hypoxiaS. M. Yagubova0Azerbaijan medical universityThe aim of the study was to study the characteristic features of ultrastructural changes in the cellular and extracellular matrix of the adrenal and thyroid glands in chronic hypoxia.Materials and methods. The study used the thyroid and adrenal glands of healthy adult male white rats weighing 180-200 g. The anatomical, histological, histochemical, electron microscopic and morphometric methods were used.Results. We found that the response of thyroid and adrenal cells to hypoxia is different. So, since the processes of proliferation in the cells of the thyroid gland occur faster and earlier, all tissues are restored on the 15th day of the experiment in the thyroid gland, and in the adrenal gland are restored only on the 30th day of the experiment. And this can be regarded as a higher degree of sensitivity of the adrenal glands to hypoxia, which is a stronger stress factor than the thyroid gland.Summary. The structures of the thyroid gland adapt to long-term hypoxia earlier, and responds to this with ultrastructural rearrangement – hyperplasia, hypertrophy and proliferation of thyrocytes.https://vestnik.reaviz.ru/jour/article/view/318electron microscopychronic hypoxiacortical and medullary substance of the adrenal glandsfollicles and thyrocytes of thyroid gland
spellingShingle S. M. Yagubova
Electron-microscopic features of changes in the adrenal and thyroid glands in chronic hypoxia
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
electron microscopy
chronic hypoxia
cortical and medullary substance of the adrenal glands
follicles and thyrocytes of thyroid gland
title Electron-microscopic features of changes in the adrenal and thyroid glands in chronic hypoxia
title_full Electron-microscopic features of changes in the adrenal and thyroid glands in chronic hypoxia
title_fullStr Electron-microscopic features of changes in the adrenal and thyroid glands in chronic hypoxia
title_full_unstemmed Electron-microscopic features of changes in the adrenal and thyroid glands in chronic hypoxia
title_short Electron-microscopic features of changes in the adrenal and thyroid glands in chronic hypoxia
title_sort electron microscopic features of changes in the adrenal and thyroid glands in chronic hypoxia
topic electron microscopy
chronic hypoxia
cortical and medullary substance of the adrenal glands
follicles and thyrocytes of thyroid gland
url https://vestnik.reaviz.ru/jour/article/view/318
work_keys_str_mv AT smyagubova electronmicroscopicfeaturesofchangesintheadrenalandthyroidglandsinchronichypoxia