MOntelukast as a potential CHondroprotective treatment following Anterior cruciate ligament reconstruction (MOCHA Trial): study protocol for a double-blind, randomized, placebo-controlled clinical trial

MOntelukast as a potential CHondroprotective treatment following Anterior cruciate ligament reconstruction (MOCHA Trial): study protocol for a double-blind, randomized, placebo-controlled clinical trial

Abstract Background After anterior cruciate ligament (ACL) reconstruction, patient-reported outcomes are improved 10 years post-surgery; however, cytokine concentrations remain elevated years after surgery with over 80% of those with combined ACL and meniscus injuries having posttraumatic osteoarthr...

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Bibliographic Details
Main Authors: Cale A. Jacobs, Caitlin E. W. Conley, Virginia Byers Kraus, Drew A. Lansdown, Brian C. Lau, Xiaojuan Li, Sharmila Majumdar, Kurt P. Spindler, Nicole G. Lemaster, Austin V. Stone
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Trials
Subjects:
Anterior cruciate ligament
Montelukast
Posttraumatic osteoarthritis
MRI
Biomarker
Online Access:https://doi.org/10.1186/s13063-021-05982-3

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