Isolation, Characterization and Structure Elucidation of a Novel Lantibiotic From Paenibacillus sp.

Isolation, Characterization and Structure Elucidation of a Novel Lantibiotic From Paenibacillus sp.

We have isolated and characterized a novel antibacterial peptide, CMB001, following an extensive screening effort of bacterial species isolated from diverse environmental sources. The bacterium that produces CMB001 is characterized as a Gram (+) bacillus sharing approximately 98.9% 16S rRNA sequence...

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Bibliographic Details
Main Authors: Jerzy Karczewski, Stephen P. Krasucki, Papa Nii Asare-Okai, Carl Diehl, Andrew Friedman, Christine M. Brown, Yukari Maezato, Stephen J. Streatfield
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial peptide
lantibiotic
NMR
stability
antibiotic resistance
MRSA
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.598789/full

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