Nitrous Oxide and Nitrous Oxide-Free Low-Flow Anesthesia Using Bispectral Index Monitoring: Effects on Hemodynamics, Recovery Times, Volatile Anesthetic Consumption and Costs
Aim: In this study, we aimed to compare the effects of desfluraneN2O and desflurane-fentanyl combinations on hemodynamics, recovery times, volatile anesthetic consumption and costs in low-flow desflurane anesthesia by bispectral index (BIS) monitoring of depth of anesthesia. Methods: After appr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2010-12-01
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| Series: | Haseki Tıp Bülteni |
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| Online Access: | http://www.hasekidergisi.com/makale_4592/Bispektral-Indeks-Monitorizasyonu-Esliginde-Azot-Protoksitli-Ve-Azot-Protoksitsiz-Dusuk-Akimli-Anestezi-Hemodinami-Derlenme-Volatil-Anestezik-Tuketimi-Ve-Maliyet-Uzerine-Etkileri-Ozgun-Arastirma |
| _version_ | 1828030954936991744 |
|---|---|
| author | Bengü Gülhan Köksal Volkan Hanc› Gülay Erdo¤an |
| author_facet | Bengü Gülhan Köksal Volkan Hanc› Gülay Erdo¤an |
| author_sort | Bengü Gülhan Köksal |
| collection | DOAJ |
| description | Aim: In this study, we aimed to compare the effects of desfluraneN2O
and desflurane-fentanyl combinations on hemodynamics,
recovery times, volatile anesthetic consumption and costs in low-flow
desflurane anesthesia by bispectral index (BIS) monitoring of depth
of anesthesia.
Methods: After approval of ethics committee and obtaining patient
consents, 60 patients were divided into two equal groups randomly.
Non-invasive blood pressure measurement, ECG, SpO2 and BIS were
monitored. All patients received 10 L .min-1 100% oxygen with mask
for 5 minute before intubation. 2 mg.kg-1 propofol, 2 μg.kg-1 fentanyl
and 0.6 mg.kg-1 rocuronium bromide were administered at
induction in both groups. Desfluran 6% was chosen for anesthesia
maintenance. Group 1 received 50% O2-N2O mixture in 6 L.min-1
and Group 2 received 50% O2-air mixture in 6 L.min-1 as carrier gas.
Low-flow anesthesia (1 L.min-1) was started after a 10-min period of
initial high flow (6 L.min-1). In Group 2, infusion of fentanyl was
begun in 1 μg.kg.hour-1 rate. Desflurane level was adjusted at a main
BIS value of 40-60. Blood pressure, heart rate, FiO2, etO2, FiN22,
EtN2O, FiCO2, EtCO2, Fidesfluran and Etdesflurane were recorded.
Results: There were no significant differences between the two
groups in terms of heart rate, arterial blood pressure, settings of
desfluran and recovery time. BIS values (p<0.001) and anesthetic
agent costs (p<0.001) were higher in Group 2.
Conclusion: Using fentanyl infusion instead of nitrous oxide in low
flow-anesthesia with desflurane did not alter the hemodynamic
parameters. Fentanyl infusion with medical air-oxygen as carrier gas
is an alternative technique, but increases BIS values and anesthetic
agent costs. (The Medical Bulletin of Haseki 2010; 48: 132-8) |
| first_indexed | 2024-04-10T14:37:10Z |
| format | Article |
| id | doaj.art-5336931890ae47ba818dda5d79b4bc44 |
| institution | Directory Open Access Journal |
| issn | 1302-0072 2147-2688 |
| language | English |
| last_indexed | 2024-04-10T14:37:10Z |
| publishDate | 2010-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-5336931890ae47ba818dda5d79b4bc442023-02-15T16:08:26ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882010-12-01484132138Nitrous Oxide and Nitrous Oxide-Free Low-Flow Anesthesia Using Bispectral Index Monitoring: Effects on Hemodynamics, Recovery Times, Volatile Anesthetic Consumption and CostsBengü Gülhan Köksal0Volkan Hanc›1Gülay Erdo¤an2Zonguldak Karaelmas Üniversitesi, T›p Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dal›, Zonguldak, TürkiyeZonguldak Karaelmas Üniversitesi, T›p Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dal›, Zonguldak, TürkiyeZonguldak Karaelmas Üniversitesi, T›p Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dal›, Zonguldak, TürkiyeAim: In this study, we aimed to compare the effects of desfluraneN2O and desflurane-fentanyl combinations on hemodynamics, recovery times, volatile anesthetic consumption and costs in low-flow desflurane anesthesia by bispectral index (BIS) monitoring of depth of anesthesia. Methods: After approval of ethics committee and obtaining patient consents, 60 patients were divided into two equal groups randomly. Non-invasive blood pressure measurement, ECG, SpO2 and BIS were monitored. All patients received 10 L .min-1 100% oxygen with mask for 5 minute before intubation. 2 mg.kg-1 propofol, 2 μg.kg-1 fentanyl and 0.6 mg.kg-1 rocuronium bromide were administered at induction in both groups. Desfluran 6% was chosen for anesthesia maintenance. Group 1 received 50% O2-N2O mixture in 6 L.min-1 and Group 2 received 50% O2-air mixture in 6 L.min-1 as carrier gas. Low-flow anesthesia (1 L.min-1) was started after a 10-min period of initial high flow (6 L.min-1). In Group 2, infusion of fentanyl was begun in 1 μg.kg.hour-1 rate. Desflurane level was adjusted at a main BIS value of 40-60. Blood pressure, heart rate, FiO2, etO2, FiN22, EtN2O, FiCO2, EtCO2, Fidesfluran and Etdesflurane were recorded. Results: There were no significant differences between the two groups in terms of heart rate, arterial blood pressure, settings of desfluran and recovery time. BIS values (p<0.001) and anesthetic agent costs (p<0.001) were higher in Group 2. Conclusion: Using fentanyl infusion instead of nitrous oxide in low flow-anesthesia with desflurane did not alter the hemodynamic parameters. Fentanyl infusion with medical air-oxygen as carrier gas is an alternative technique, but increases BIS values and anesthetic agent costs. (The Medical Bulletin of Haseki 2010; 48: 132-8)http://www.hasekidergisi.com/makale_4592/Bispektral-Indeks-Monitorizasyonu-Esliginde-Azot-Protoksitli-Ve-Azot-Protoksitsiz-Dusuk-Akimli-Anestezi-Hemodinami-Derlenme-Volatil-Anestezik-Tuketimi-Ve-Maliyet-Uzerine-Etkileri-Ozgun-Arastirmaow-flow anesthesiadesfluraneN2OBISanesthetic gas costs. |
| spellingShingle | Bengü Gülhan Köksal Volkan Hanc› Gülay Erdo¤an Nitrous Oxide and Nitrous Oxide-Free Low-Flow Anesthesia Using Bispectral Index Monitoring: Effects on Hemodynamics, Recovery Times, Volatile Anesthetic Consumption and Costs Haseki Tıp Bülteni ow-flow anesthesia desflurane N2O BIS anesthetic gas costs. |
| title | Nitrous Oxide and Nitrous Oxide-Free Low-Flow Anesthesia Using Bispectral Index Monitoring: Effects on Hemodynamics, Recovery Times, Volatile Anesthetic Consumption and Costs |
| title_full | Nitrous Oxide and Nitrous Oxide-Free Low-Flow Anesthesia Using Bispectral Index Monitoring: Effects on Hemodynamics, Recovery Times, Volatile Anesthetic Consumption and Costs |
| title_fullStr | Nitrous Oxide and Nitrous Oxide-Free Low-Flow Anesthesia Using Bispectral Index Monitoring: Effects on Hemodynamics, Recovery Times, Volatile Anesthetic Consumption and Costs |
| title_full_unstemmed | Nitrous Oxide and Nitrous Oxide-Free Low-Flow Anesthesia Using Bispectral Index Monitoring: Effects on Hemodynamics, Recovery Times, Volatile Anesthetic Consumption and Costs |
| title_short | Nitrous Oxide and Nitrous Oxide-Free Low-Flow Anesthesia Using Bispectral Index Monitoring: Effects on Hemodynamics, Recovery Times, Volatile Anesthetic Consumption and Costs |
| title_sort | nitrous oxide and nitrous oxide free low flow anesthesia using bispectral index monitoring effects on hemodynamics recovery times volatile anesthetic consumption and costs |
| topic | ow-flow anesthesia desflurane N2O BIS anesthetic gas costs. |
| url | http://www.hasekidergisi.com/makale_4592/Bispektral-Indeks-Monitorizasyonu-Esliginde-Azot-Protoksitli-Ve-Azot-Protoksitsiz-Dusuk-Akimli-Anestezi-Hemodinami-Derlenme-Volatil-Anestezik-Tuketimi-Ve-Maliyet-Uzerine-Etkileri-Ozgun-Arastirma |
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