The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin D
The article presents the results of the genome-wide bioinformatic analysis of the vitamin D receptor interactions with the human genome DNA. Using a biological system assay, biological roles of proteins were analyzed that are specifically associated with the impact of VDR receptor. Systematization o...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2016-12-01
|
| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/3 |
| _version_ | 1797842035186597888 |
|---|---|
| author | O. A. Gromova I. Y. Torshin V. B. Spirichev |
| author_facet | O. A. Gromova I. Y. Torshin V. B. Spirichev |
| author_sort | O. A. Gromova |
| collection | DOAJ |
| description | The article presents the results of the genome-wide bioinformatic analysis of the vitamin D receptor interactions with the human genome DNA. Using a biological system assay, biological roles of proteins were analyzed that are specifically associated with the impact of VDR receptor. Systematization of the biological roles of vitamin D opens broad and previously unexplored perspectives for pediatric applications of vitamin D preparations for the prevention and treatment of a wide range of diseases starting from the fetal stage and early childhood. |
| first_indexed | 2024-04-09T16:41:21Z |
| format | Article |
| id | doaj.art-533a672a51344025844d662876dbd321 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:41:21Z |
| publishDate | 2016-12-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-533a672a51344025844d662876dbd3212023-04-23T06:56:40ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902016-12-0111122110.21518/2079-701X-2016-1-12-213The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin DO. A. Gromova0I. Y. Torshin1V. B. Spirichev2Ivanovo State Medical AcademyMoscow Institute of Physics and TechnologyScientific Research Institute of NutritionThe article presents the results of the genome-wide bioinformatic analysis of the vitamin D receptor interactions with the human genome DNA. Using a biological system assay, biological roles of proteins were analyzed that are specifically associated with the impact of VDR receptor. Systematization of the biological roles of vitamin D opens broad and previously unexplored perspectives for pediatric applications of vitamin D preparations for the prevention and treatment of a wide range of diseases starting from the fetal stage and early childhood.https://www.med-sovet.pro/jour/article/view/3геномные эффекты витамина dэпигенетикадетипрофилактика дефицита витамина dgenomic effects of vitamin depigeneticschildrenprevention of vitamin d deficiency |
| spellingShingle | O. A. Gromova I. Y. Torshin V. B. Spirichev The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin D Медицинский совет геномные эффекты витамина d эпигенетика дети профилактика дефицита витамина d genomic effects of vitamin d epigenetics children prevention of vitamin d deficiency |
| title | The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin D |
| title_full | The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin D |
| title_fullStr | The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin D |
| title_full_unstemmed | The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin D |
| title_short | The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin D |
| title_sort | genome wide analysis of the vitamin d receptor binding sites evidences a wide range of potential therapeutic applications of vitamin d |
| topic | геномные эффекты витамина d эпигенетика дети профилактика дефицита витамина d genomic effects of vitamin d epigenetics children prevention of vitamin d deficiency |
| url | https://www.med-sovet.pro/jour/article/view/3 |
| work_keys_str_mv | AT oagromova thegenomewideanalysisofthevitamindreceptorbindingsitesevidencesawiderangeofpotentialtherapeuticapplicationsofvitamind AT iytorshin thegenomewideanalysisofthevitamindreceptorbindingsitesevidencesawiderangeofpotentialtherapeuticapplicationsofvitamind AT vbspirichev thegenomewideanalysisofthevitamindreceptorbindingsitesevidencesawiderangeofpotentialtherapeuticapplicationsofvitamind AT oagromova genomewideanalysisofthevitamindreceptorbindingsitesevidencesawiderangeofpotentialtherapeuticapplicationsofvitamind AT iytorshin genomewideanalysisofthevitamindreceptorbindingsitesevidencesawiderangeofpotentialtherapeuticapplicationsofvitamind AT vbspirichev genomewideanalysisofthevitamindreceptorbindingsitesevidencesawiderangeofpotentialtherapeuticapplicationsofvitamind |