An insight into the anti-inflammatory properties of edible and medicinal mushrooms

Background: Mushrooms have been valuable as edible and medical provisions for humankind. It is attributed not only to the quality of their taste but also to their biological activities. The extracts, compounds, and metabolites have a lot of biological activities such as antidiabetic, antioxidative,...

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Main Authors: Bin Du, Fengmei Zhu, Baojun Xu
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618302998
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author Bin Du
Fengmei Zhu
Baojun Xu
author_facet Bin Du
Fengmei Zhu
Baojun Xu
author_sort Bin Du
collection DOAJ
description Background: Mushrooms have been valuable as edible and medical provisions for humankind. It is attributed not only to the quality of their taste but also to their biological activities. The extracts, compounds, and metabolites have a lot of biological activities such as antidiabetic, antioxidative, antitumor, and anti-inflammatory effects. The potent anti-inflammatory activity is associated with a multitude of signaling pathways. However, there are a few review papers on the anti-inflammatory activity of mushrooms. Scope and approach: Herein, the anti-inflammatory potential of mushroom is critically discussed using in vitro and animal models. Moreover, the mechanisms of anti-inflammatory activity are summarized. The current status of clinical studies evaluating anti-inflammatory activity of mushroom is also presented. Key findings and conclusion: It is believed that insights about these advances may encourage researchers to discover new phytochemical components and further study specific bioactivities of mushroom.
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spelling doaj.art-533f8c37cc94422881b9b5d471af18902022-12-21T19:16:48ZengElsevierJournal of Functional Foods1756-46462018-08-0147334342An insight into the anti-inflammatory properties of edible and medicinal mushroomsBin Du0Fengmei Zhu1Baojun Xu2Hebei Normal University of Science and Technology, Qinhuangdao, Hebei 066600, ChinaHebei Normal University of Science and Technology, Qinhuangdao, Hebei 066600, ChinaFood Science and Technology Program, Beijing Normal University–Hong Kong Baptist University United International College, Zhuhai, Guangdong 519087, China; Corresponding author at: 2000, Jintong Road, Tangjiawan, Zhuhai, Guangdong 519087, China.Background: Mushrooms have been valuable as edible and medical provisions for humankind. It is attributed not only to the quality of their taste but also to their biological activities. The extracts, compounds, and metabolites have a lot of biological activities such as antidiabetic, antioxidative, antitumor, and anti-inflammatory effects. The potent anti-inflammatory activity is associated with a multitude of signaling pathways. However, there are a few review papers on the anti-inflammatory activity of mushrooms. Scope and approach: Herein, the anti-inflammatory potential of mushroom is critically discussed using in vitro and animal models. Moreover, the mechanisms of anti-inflammatory activity are summarized. The current status of clinical studies evaluating anti-inflammatory activity of mushroom is also presented. Key findings and conclusion: It is believed that insights about these advances may encourage researchers to discover new phytochemical components and further study specific bioactivities of mushroom.http://www.sciencedirect.com/science/article/pii/S1756464618302998MushroomAnti-inflammatory activityIn vitro modelAnimal modelChemopreventive propertyTherapeutic potential
spellingShingle Bin Du
Fengmei Zhu
Baojun Xu
An insight into the anti-inflammatory properties of edible and medicinal mushrooms
Journal of Functional Foods
Mushroom
Anti-inflammatory activity
In vitro model
Animal model
Chemopreventive property
Therapeutic potential
title An insight into the anti-inflammatory properties of edible and medicinal mushrooms
title_full An insight into the anti-inflammatory properties of edible and medicinal mushrooms
title_fullStr An insight into the anti-inflammatory properties of edible and medicinal mushrooms
title_full_unstemmed An insight into the anti-inflammatory properties of edible and medicinal mushrooms
title_short An insight into the anti-inflammatory properties of edible and medicinal mushrooms
title_sort insight into the anti inflammatory properties of edible and medicinal mushrooms
topic Mushroom
Anti-inflammatory activity
In vitro model
Animal model
Chemopreventive property
Therapeutic potential
url http://www.sciencedirect.com/science/article/pii/S1756464618302998
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