Farnesylthiosalicylic acid sensitizes hepatocarcinoma cells to artemisinin derivatives.

Farnesylthiosalicylic acid sensitizes hepatocarcinoma cells to artemisinin derivatives.

Dihydroartemisinin (DHA) and artesunate (ARS), two artemisinin derivatives, have efficacious anticancer activities against human hepatocarcinoma (HCC) cells. This study aims to study the anticancer action of the combination treatment of DHA/ARS and farnesylthiosalicylic acid (FTS), a Ras inhibitor,...

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Bibliographic Details
Main Authors: Liping Wu, Yilin Pang, Guiqi Qin, Gaina Xi, Shengnan Wu, Xiaoping Wang, Tongsheng Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5300221?pdf=render

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