Autophagy Function and Dysfunction: Potential Drugs as Anti-Cancer Therapy
Autophagy is a highly conserved catabolic and energy-generating process that facilitates the degradation of damaged organelles or intracellular components, providing cells with components for the synthesis of new ones. Autophagy acts as a quality control system, and has a pro-survival role. The imba...
Main Authors: | Francesca Cuomo, Lucia Altucci, Gilda Cobellis |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/10/1465 |
Similar Items
-
The Autophagy Inhibitor Chloroquine, Alone or in Combination with mTOR Inhibitors, Displays Anti-Tumor Effects in In Vitro and In Vivo Lung Carcinoid Models
by: Adi Knigin, et al.
Published: (2021-12-01) -
Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models
by: Stefania Cocco, et al.
Published: (2022-06-01) -
Effects of chloroquine on proliferation, apoptosis and autophagy of human cervical cancer cell line HeLa
by: GAO Peng, XU Dandan, ZHANG Bin, LIU Xuntao, SHU Lisha
Published: (2023-10-01) -
Inhibition of Autophagy Does Not Re-Sensitize Acute Myeloid Leukemia Cells Resistant to Cytarabine
by: Nienke Visser, et al.
Published: (2021-02-01) -
Chloroquine Inhibition of Autophagy Enhanced the Anticancer Effects of <i>Listeria monocytogenes</i> in Melanoma
by: Zuhua Yu, et al.
Published: (2023-02-01)