Evaluation of Thyroid Function Status in Polycystic Ovary Syndrome
Background: PCOS is very commonly seen in young females with chronic anovulatory cycles. It is manifested by features of hyperandrogenism, polycystic ovaries. The risk of insulin resistance is greater in patients with PCOS. There is also a greater incidence of type 2 diabetes, obesity and cardio...
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| Format: | Article |
| Language: | English |
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Prathima Institute of Medical Sciences
2020-04-01
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| Series: | Perspectives In Medical Research |
| Subjects: | |
| Online Access: | https://www.pimr.org.in/2020-vol8-issue-1/originalarticle6_v1.pdf |
| _version_ | 1797462449861951488 |
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| author | Dr. Syeda Sobia Harmain1 , Dr. Mohd Inayatulla Khan2 |
| author_facet | Dr. Syeda Sobia Harmain1 , Dr. Mohd Inayatulla Khan2 |
| author_sort | Dr. Syeda Sobia Harmain1 , Dr. Mohd Inayatulla Khan2 |
| collection | DOAJ |
| description | Background: PCOS is very commonly seen in young females
with chronic anovulatory cycles. It is manifested by features of
hyperandrogenism, polycystic ovaries. The risk of insulin
resistance is greater in patients with PCOS. There is also a
greater incidence of type 2 diabetes, obesity and cardiovascular
diseases in patients with PCOS. There are associated endocrinal
abnormalities with PCOS most common of which include
hypothyroidism. Therefore we in the present study tried to
evaluate the existence of hypothyroidism in patients with PCOS
in the patients reporting to our Hospital.
Methods: The present study was conducted in the Department
of Obstetrics and gynecology, MGM Hospital and Kakatiya
Medical College, Warangal. Institutional Ethical committee
permission was obtained for the study. The duration of the
study was from January 2018 to May 2019. N=30 patients were
detected with PCOS during the study period. A similar number
of age-matched controls without PCOS were taken for
comparison. Anthropometric measurements were made for
BMI, waist-hip ratio calculation. TSH, FSH, LH, and Testosterone
were estimated by Chemiluminescence ImmunoAssay (CLIA)
technique.
Results: The Mean Bodyweight 62.17 Vs 49.33 Kgs, The mean
BMI was 24.03 Vs 22.48 Kg/m2. The mean TSH values were
5.33 Vs 2.51 µIU/ml. The mean FSH values were 12.27 Vs 8.49
µIU/ml the mean LH was 4.27 Vs 10.49 µIU/ml and the mean
Testosterone levels were 69.73 Vs 9.28 ng/ml.
Conclusion: The present study concludes that patients with
PCOS have a greater frequency of thyroid dysfunctions
including other endocrinal abnormalities. Accordingly, those
diagnosed with PCOS must undergo complete endocrinal
investigations. This can help to identify the co-existing
endocrinal abnormalities and treatment is given accordingly
to prevent morbidity and mortality |
| first_indexed | 2024-03-09T17:36:45Z |
| format | Article |
| id | doaj.art-53451b15079d4845a663e31dded5cf69 |
| institution | Directory Open Access Journal |
| issn | 2348-1447 2348-229X |
| language | English |
| last_indexed | 2024-03-09T17:36:45Z |
| publishDate | 2020-04-01 |
| publisher | Prathima Institute of Medical Sciences |
| record_format | Article |
| series | Perspectives In Medical Research |
| spelling | doaj.art-53451b15079d4845a663e31dded5cf692023-11-24T11:52:41ZengPrathima Institute of Medical SciencesPerspectives In Medical Research2348-14472348-229X2020-04-01813842Evaluation of Thyroid Function Status in Polycystic Ovary SyndromeDr. Syeda Sobia Harmain1 , Dr. Mohd Inayatulla Khan20PG, Department of Physiology, Kakatiya Medical College and MGM Hospital, Warangal, Telangana State. 2 Assistant Professor, Department of Physiology, Rajiv Gandhi Institute of Medical Sciences [RIMS], Adilabad, Telangana State. Address for communication: Dr. Mohd Inayatulla Khan, Department of Physiology, Rajiv Gandhi Institute of Medical Sciences, Adilabad-504001, Telangana State, India. Email: drkhan123@rediffmail.comBackground: PCOS is very commonly seen in young females with chronic anovulatory cycles. It is manifested by features of hyperandrogenism, polycystic ovaries. The risk of insulin resistance is greater in patients with PCOS. There is also a greater incidence of type 2 diabetes, obesity and cardiovascular diseases in patients with PCOS. There are associated endocrinal abnormalities with PCOS most common of which include hypothyroidism. Therefore we in the present study tried to evaluate the existence of hypothyroidism in patients with PCOS in the patients reporting to our Hospital. Methods: The present study was conducted in the Department of Obstetrics and gynecology, MGM Hospital and Kakatiya Medical College, Warangal. Institutional Ethical committee permission was obtained for the study. The duration of the study was from January 2018 to May 2019. N=30 patients were detected with PCOS during the study period. A similar number of age-matched controls without PCOS were taken for comparison. Anthropometric measurements were made for BMI, waist-hip ratio calculation. TSH, FSH, LH, and Testosterone were estimated by Chemiluminescence ImmunoAssay (CLIA) technique. Results: The Mean Bodyweight 62.17 Vs 49.33 Kgs, The mean BMI was 24.03 Vs 22.48 Kg/m2. The mean TSH values were 5.33 Vs 2.51 µIU/ml. The mean FSH values were 12.27 Vs 8.49 µIU/ml the mean LH was 4.27 Vs 10.49 µIU/ml and the mean Testosterone levels were 69.73 Vs 9.28 ng/ml. Conclusion: The present study concludes that patients with PCOS have a greater frequency of thyroid dysfunctions including other endocrinal abnormalities. Accordingly, those diagnosed with PCOS must undergo complete endocrinal investigations. This can help to identify the co-existing endocrinal abnormalities and treatment is given accordingly to prevent morbidity and mortalityhttps://www.pimr.org.in/2020-vol8-issue-1/originalarticle6_v1.pdfpolycystic ovary syndromethyroid functions |
| spellingShingle | Dr. Syeda Sobia Harmain1 , Dr. Mohd Inayatulla Khan2 Evaluation of Thyroid Function Status in Polycystic Ovary Syndrome Perspectives In Medical Research polycystic ovary syndrome thyroid functions |
| title | Evaluation of Thyroid Function Status in Polycystic Ovary Syndrome |
| title_full | Evaluation of Thyroid Function Status in Polycystic Ovary Syndrome |
| title_fullStr | Evaluation of Thyroid Function Status in Polycystic Ovary Syndrome |
| title_full_unstemmed | Evaluation of Thyroid Function Status in Polycystic Ovary Syndrome |
| title_short | Evaluation of Thyroid Function Status in Polycystic Ovary Syndrome |
| title_sort | evaluation of thyroid function status in polycystic ovary syndrome |
| topic | polycystic ovary syndrome thyroid functions |
| url | https://www.pimr.org.in/2020-vol8-issue-1/originalarticle6_v1.pdf |
| work_keys_str_mv | AT drsyedasobiaharmain1drmohdinayatullakhan2 evaluationofthyroidfunctionstatusinpolycysticovarysyndrome |