Distribution characteristics of ABO blood groups in China
ABO blood groups distribution shows obvious geographical differences globally, but the reliability of the Blood data for assessing relationships between population groups is limited. This is mostly due to the lack of availability and interchange of this important data. We collected data of 23 millio...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022018564 |
| _version_ | 1811206285165592576 |
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| author | Yang Sun Liqin Wang Jiameng Niu Ting Ma Lili Xing Aowei Song Wenhua Wang Yuan Shen Jiangcun Yang |
| author_facet | Yang Sun Liqin Wang Jiameng Niu Ting Ma Lili Xing Aowei Song Wenhua Wang Yuan Shen Jiangcun Yang |
| author_sort | Yang Sun |
| collection | DOAJ |
| description | ABO blood groups distribution shows obvious geographical differences globally, but the reliability of the Blood data for assessing relationships between population groups is limited. This is mostly due to the lack of availability and interchange of this important data. We collected data of 23 million ABO blood group population from 34 provincial-level administrative regions in China. To ensure the reliability of the results, we standardized the 23 million data by the China seventh census data. The ranking of ABO blood groups phenotypic distribution in China is O > A > B > AB. The proportions of A, B, O and AB type in China population are 28.72%, 28.17%, 34.20%, and 8.91%, respectively. Accordingly, the frequencies of p [A], q [B], and r [O] gene at the ABO blood group are 0.211, 0.208, and 0.584, respectively. China blood phenotype is dominated by O type, but the r gene frequency is obviously lower than other countries. The distribution of ABO blood groups in China varies geographically. Clustering analysis results show that ABO blood groups divide into four regions from north to south in China, and reveal that the r [O] gene shows an increasing trend from North to South, and conversely the q [B] gene exhibited a decreasing trend at these coordinates. These analyses present interesting characteristics of the blood group distribution across the geography of China. |
| first_indexed | 2024-04-12T03:46:17Z |
| format | Article |
| id | doaj.art-5345d935b24c4e098c59cbbcec0eb607 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-12T03:46:17Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-5345d935b24c4e098c59cbbcec0eb6072022-12-22T03:49:08ZengElsevierHeliyon2405-84402022-09-0189e10568Distribution characteristics of ABO blood groups in ChinaYang Sun0Liqin Wang1Jiameng Niu2Ting Ma3Lili Xing4Aowei Song5Wenhua Wang6Yuan Shen7Jiangcun Yang8Data Center, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, ChinaDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, ChinaDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, ChinaDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, ChinaDepartment of Transfusion Medicine, Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, ChinaDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, ChinaDepartment of Transfusion Medicine, Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China; Corresponding author.Department of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China; Corresponding author.ABO blood groups distribution shows obvious geographical differences globally, but the reliability of the Blood data for assessing relationships between population groups is limited. This is mostly due to the lack of availability and interchange of this important data. We collected data of 23 million ABO blood group population from 34 provincial-level administrative regions in China. To ensure the reliability of the results, we standardized the 23 million data by the China seventh census data. The ranking of ABO blood groups phenotypic distribution in China is O > A > B > AB. The proportions of A, B, O and AB type in China population are 28.72%, 28.17%, 34.20%, and 8.91%, respectively. Accordingly, the frequencies of p [A], q [B], and r [O] gene at the ABO blood group are 0.211, 0.208, and 0.584, respectively. China blood phenotype is dominated by O type, but the r gene frequency is obviously lower than other countries. The distribution of ABO blood groups in China varies geographically. Clustering analysis results show that ABO blood groups divide into four regions from north to south in China, and reveal that the r [O] gene shows an increasing trend from North to South, and conversely the q [B] gene exhibited a decreasing trend at these coordinates. These analyses present interesting characteristics of the blood group distribution across the geography of China.http://www.sciencedirect.com/science/article/pii/S2405844022018564China populationABO blood groupPhenotypeGene frequencyDistribution characteristics |
| spellingShingle | Yang Sun Liqin Wang Jiameng Niu Ting Ma Lili Xing Aowei Song Wenhua Wang Yuan Shen Jiangcun Yang Distribution characteristics of ABO blood groups in China Heliyon China population ABO blood group Phenotype Gene frequency Distribution characteristics |
| title | Distribution characteristics of ABO blood groups in China |
| title_full | Distribution characteristics of ABO blood groups in China |
| title_fullStr | Distribution characteristics of ABO blood groups in China |
| title_full_unstemmed | Distribution characteristics of ABO blood groups in China |
| title_short | Distribution characteristics of ABO blood groups in China |
| title_sort | distribution characteristics of abo blood groups in china |
| topic | China population ABO blood group Phenotype Gene frequency Distribution characteristics |
| url | http://www.sciencedirect.com/science/article/pii/S2405844022018564 |
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