Liesegang rings in the setting of end‐stage renal disease

Introduction Liesegang rings are acellular, lamellar, concentric rings of organic or inorganic material naturally formed in both biologic and environmental systems. Description in human tissue is scarce. Liesegang rings have exclusively been identified in association with pathologic disease processe...

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Main Authors: Alexander R Gross, Shahrier Amin, Tomislav Jelic
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:IJU Case Reports
Subjects:
Online Access:https://doi.org/10.1002/iju5.12494
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author Alexander R Gross
Shahrier Amin
Tomislav Jelic
author_facet Alexander R Gross
Shahrier Amin
Tomislav Jelic
author_sort Alexander R Gross
collection DOAJ
description Introduction Liesegang rings are acellular, lamellar, concentric rings of organic or inorganic material naturally formed in both biologic and environmental systems. Description in human tissue is scarce. Liesegang rings have exclusively been identified in association with pathologic disease processes and thus are not typically considered in differential diagnosis. They are usually described with cystic or inflammatory lesions. Histologically, Liesegang rings show features that are also seen in sections of parasitic ova, larvae, psammoma bodies, and by radiology as calcifications in cystic diseases of the breast and kidney. Case presentation We noted at autopsy of a 59‐year‐old diabetic woman multiple black “stones” in the renal medulla. Microscopic examination demonstrated these to contain Liesegang rings. Conclusion Liesegang rings formation should be considered in the differential diagnosis of atypical appearing deposits in the kidneys and other tissues. They may play a role in the pathogenesis of kidney stones.
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spelling doaj.art-53474b5f3d4345679249a07d18568f952022-12-22T04:35:09ZengWileyIJU Case Reports2577-171X2022-11-015642342610.1002/iju5.12494Liesegang rings in the setting of end‐stage renal diseaseAlexander R Gross0Shahrier Amin1Tomislav Jelic2Department of Pathology Anatomy, and Laboratory Medicine WVU Robert C Byrd Health Sciences Center Morgantown West Virginia USADepartment of Pathology Anatomy, and Laboratory Medicine WVU Robert C Byrd Health Sciences Center Morgantown West Virginia USADepartment of Pathology Charleston Area Medical Center Charleston West Virginia USAIntroduction Liesegang rings are acellular, lamellar, concentric rings of organic or inorganic material naturally formed in both biologic and environmental systems. Description in human tissue is scarce. Liesegang rings have exclusively been identified in association with pathologic disease processes and thus are not typically considered in differential diagnosis. They are usually described with cystic or inflammatory lesions. Histologically, Liesegang rings show features that are also seen in sections of parasitic ova, larvae, psammoma bodies, and by radiology as calcifications in cystic diseases of the breast and kidney. Case presentation We noted at autopsy of a 59‐year‐old diabetic woman multiple black “stones” in the renal medulla. Microscopic examination demonstrated these to contain Liesegang rings. Conclusion Liesegang rings formation should be considered in the differential diagnosis of atypical appearing deposits in the kidneys and other tissues. They may play a role in the pathogenesis of kidney stones.https://doi.org/10.1002/iju5.12494diabetic proteinuriakidney stonesliesegang rings
spellingShingle Alexander R Gross
Shahrier Amin
Tomislav Jelic
Liesegang rings in the setting of end‐stage renal disease
IJU Case Reports
diabetic proteinuria
kidney stones
liesegang rings
title Liesegang rings in the setting of end‐stage renal disease
title_full Liesegang rings in the setting of end‐stage renal disease
title_fullStr Liesegang rings in the setting of end‐stage renal disease
title_full_unstemmed Liesegang rings in the setting of end‐stage renal disease
title_short Liesegang rings in the setting of end‐stage renal disease
title_sort liesegang rings in the setting of end stage renal disease
topic diabetic proteinuria
kidney stones
liesegang rings
url https://doi.org/10.1002/iju5.12494
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