TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves

TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves

Previously we showed that the hippo pathway transcriptional effectors, YAP and TAZ, are essential for Schwann cells (SCs) to develop, maintain and regenerate myelin . Although TEAD1 has been implicated as a partner transcription factor, the mechanisms by which it mediates YAP/TAZ regulation of SC my...

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Bibliographic Details
Main Authors: Matthew Grove, Hyukmin Kim, Shuhuan Pang, Jose Paz Amaya, Guoqing Hu, Jiliang Zhou, Michel Lemay, Young-Jin Son
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-03-01
Series:eLife
Subjects:
Schwann cells
myelination
yap
peripheral neuropathy
taz
remak
Online Access:https://elifesciences.org/articles/87394

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