Body Mass Index Is Independently Associated with the Presence of Ischemia in Myocardial Perfusion Imaging

<i>Background and Objectives</i>: Obesity has been linked to various cardiovascular risk factors, increased incidence of coronary artery disease, and myocardial perfusion defects. The aim of this study was to investigate if body mass index (BMI) and waist circumference (WC) were associat...

Full description

Bibliographic Details
Main Authors: Chrissa Sioka, Paraskevi Zotou, Michail I. Papafaklis, Aris Bechlioulis, Konstantinos Sakellariou, Aidonis Rammos, Evangelia Gkika, Lampros Lakkas, Sotiria Alexiou, Pavlos Kekiopoulos, Katerina K. Naka, Christos Katsouras
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/58/8/987
_version_ 1797408977729880064
author Chrissa Sioka
Paraskevi Zotou
Michail I. Papafaklis
Aris Bechlioulis
Konstantinos Sakellariou
Aidonis Rammos
Evangelia Gkika
Lampros Lakkas
Sotiria Alexiou
Pavlos Kekiopoulos
Katerina K. Naka
Christos Katsouras
author_facet Chrissa Sioka
Paraskevi Zotou
Michail I. Papafaklis
Aris Bechlioulis
Konstantinos Sakellariou
Aidonis Rammos
Evangelia Gkika
Lampros Lakkas
Sotiria Alexiou
Pavlos Kekiopoulos
Katerina K. Naka
Christos Katsouras
author_sort Chrissa Sioka
collection DOAJ
description <i>Background and Objectives</i>: Obesity has been linked to various cardiovascular risk factors, increased incidence of coronary artery disease, and myocardial perfusion defects. The aim of this study was to investigate if body mass index (BMI) and waist circumference (WC) were associated with myocardial perfusion defects. <i>Materials and Methods</i>: A total of 308 consecutive patients who had myocardial perfusion imaging (MPI) with single photon emission computed tomography (SPECT) and a complete medical record on file were studied retrospectively. <i>Results</i>: The median age was 69 (61–76) years, the BMI was 27.6 (24.4–30.7) kg/m<sup>2</sup>, and the WC was 110 (102–118) cm. Of the 308 patients, 239 patients (77.6%) had myocardial ischemia. A positive test for ischemia was more frequent in men compared to women (72 vs. 28%, <i>p</i> < 0.001). Within the male group, BMI and WC were not significantly different between the ischemia and non-ischemia groups. In contrast, within the female group, both BMI (30.2 vs. 27.1 kg/m<sup>2</sup>, <i>p</i> = 0.002) and WC (112 vs. 105.5 cm, <i>p</i> = 0.020) were significantly higher in the ischemia group. Multivariable logistic regression showed that male sex and BMI were the only two independent predictors of ischemia in our patient population. <i>Conclusions</i>: This study showed that BMI was an independent predictor of ischemia in our patient population.
first_indexed 2024-03-09T04:07:39Z
format Article
id doaj.art-534e03179f604547af460e9da87dd805
institution Directory Open Access Journal
issn 1010-660X
1648-9144
language English
last_indexed 2024-03-09T04:07:39Z
publishDate 2022-07-01
publisher MDPI AG
record_format Article
series Medicina
spelling doaj.art-534e03179f604547af460e9da87dd8052023-12-03T14:04:17ZengMDPI AGMedicina1010-660X1648-91442022-07-0158898710.3390/medicina58080987Body Mass Index Is Independently Associated with the Presence of Ischemia in Myocardial Perfusion ImagingChrissa Sioka0Paraskevi Zotou1Michail I. Papafaklis2Aris Bechlioulis3Konstantinos Sakellariou4Aidonis Rammos5Evangelia Gkika6Lampros Lakkas7Sotiria Alexiou8Pavlos Kekiopoulos9Katerina K. Naka10Christos Katsouras11Department of Nuclear Medicine, University Hospital of Ioannina, 45500 Ioannina, GreeceDepartment of Nuclear Medicine, University Hospital of Ioannina, 45500 Ioannina, Greece2nd Department of Cardiology, University Hospital of Ioannina, 45500 Ioannina, Greece2nd Department of Cardiology, University Hospital of Ioannina, 45500 Ioannina, GreeceDepartment of Nuclear Medicine, University Hospital of Ioannina, 45500 Ioannina, Greece2nd Department of Cardiology, University Hospital of Ioannina, 45500 Ioannina, GreeceDepartment of Nuclear Medicine, University Hospital of Ioannina, 45500 Ioannina, Greece2nd Department of Cardiology, University Hospital of Ioannina, 45500 Ioannina, GreeceDepartment of Nuclear Medicine, University Hospital of Ioannina, 45500 Ioannina, GreeceDepartment of Nuclear Medicine, University Hospital of Ioannina, 45500 Ioannina, Greece2nd Department of Cardiology, University Hospital of Ioannina, 45500 Ioannina, Greece2nd Department of Cardiology, University Hospital of Ioannina, 45500 Ioannina, Greece<i>Background and Objectives</i>: Obesity has been linked to various cardiovascular risk factors, increased incidence of coronary artery disease, and myocardial perfusion defects. The aim of this study was to investigate if body mass index (BMI) and waist circumference (WC) were associated with myocardial perfusion defects. <i>Materials and Methods</i>: A total of 308 consecutive patients who had myocardial perfusion imaging (MPI) with single photon emission computed tomography (SPECT) and a complete medical record on file were studied retrospectively. <i>Results</i>: The median age was 69 (61–76) years, the BMI was 27.6 (24.4–30.7) kg/m<sup>2</sup>, and the WC was 110 (102–118) cm. Of the 308 patients, 239 patients (77.6%) had myocardial ischemia. A positive test for ischemia was more frequent in men compared to women (72 vs. 28%, <i>p</i> < 0.001). Within the male group, BMI and WC were not significantly different between the ischemia and non-ischemia groups. In contrast, within the female group, both BMI (30.2 vs. 27.1 kg/m<sup>2</sup>, <i>p</i> = 0.002) and WC (112 vs. 105.5 cm, <i>p</i> = 0.020) were significantly higher in the ischemia group. Multivariable logistic regression showed that male sex and BMI were the only two independent predictors of ischemia in our patient population. <i>Conclusions</i>: This study showed that BMI was an independent predictor of ischemia in our patient population.https://www.mdpi.com/1648-9144/58/8/987myocardial perfusion imagingmyocardial ischemiabody mass indexwaist circumferenceobesity
spellingShingle Chrissa Sioka
Paraskevi Zotou
Michail I. Papafaklis
Aris Bechlioulis
Konstantinos Sakellariou
Aidonis Rammos
Evangelia Gkika
Lampros Lakkas
Sotiria Alexiou
Pavlos Kekiopoulos
Katerina K. Naka
Christos Katsouras
Body Mass Index Is Independently Associated with the Presence of Ischemia in Myocardial Perfusion Imaging
Medicina
myocardial perfusion imaging
myocardial ischemia
body mass index
waist circumference
obesity
title Body Mass Index Is Independently Associated with the Presence of Ischemia in Myocardial Perfusion Imaging
title_full Body Mass Index Is Independently Associated with the Presence of Ischemia in Myocardial Perfusion Imaging
title_fullStr Body Mass Index Is Independently Associated with the Presence of Ischemia in Myocardial Perfusion Imaging
title_full_unstemmed Body Mass Index Is Independently Associated with the Presence of Ischemia in Myocardial Perfusion Imaging
title_short Body Mass Index Is Independently Associated with the Presence of Ischemia in Myocardial Perfusion Imaging
title_sort body mass index is independently associated with the presence of ischemia in myocardial perfusion imaging
topic myocardial perfusion imaging
myocardial ischemia
body mass index
waist circumference
obesity
url https://www.mdpi.com/1648-9144/58/8/987
work_keys_str_mv AT chrissasioka bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT paraskevizotou bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT michailipapafaklis bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT arisbechlioulis bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT konstantinossakellariou bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT aidonisrammos bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT evangeliagkika bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT lamproslakkas bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT sotiriaalexiou bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT pavloskekiopoulos bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT katerinaknaka bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging
AT christoskatsouras bodymassindexisindependentlyassociatedwiththepresenceofischemiainmyocardialperfusionimaging