A combination of Beers and STOPP criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy: a multicenter cross-sectional study
Abstract Background Research on potentially inappropriate medications (PIM) and medication-related problems (MRP) among the Chinese population with chronic diseases and polypharmacy is insufficient. Objectives This study aimed to investigate the prevalence of PIM and MRP among older Chinese hospital...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | BMC Geriatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12877-023-03743-2 |
| _version_ | 1811175683858104320 |
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| author | Jing Tang Ke Wang Kun Yang Dechun Jiang Xianghua Fang Su Su Yang Lin Shicai Chen Hongyan Gu Pengmei Li Suying Yan |
| author_facet | Jing Tang Ke Wang Kun Yang Dechun Jiang Xianghua Fang Su Su Yang Lin Shicai Chen Hongyan Gu Pengmei Li Suying Yan |
| author_sort | Jing Tang |
| collection | DOAJ |
| description | Abstract Background Research on potentially inappropriate medications (PIM) and medication-related problems (MRP) among the Chinese population with chronic diseases and polypharmacy is insufficient. Objectives This study aimed to investigate the prevalence of PIM and MRP among older Chinese hospitalized patients with chronic diseases and polypharmacy and analyze the associated factors. Methods A retrospective cross-sectional study was conducted in five tertiary hospitals in Beijing. Patients aged ≥ 65 years with at least one chronic disease and taking at least five or more medications were included. Data were extracted from the hospitals’ electronic medical record systems. PIM was evaluated according to the 2015 Beers criteria and the 2014 Screening Tool of Older Persons’ Prescriptions (STOPP) criteria. MRPs were assessed and classified according to the Helper-Strand classification system. The prevalence of PIM and MRP and related factors were analyzed. Results A total of 852 cases were included. The prevalence of PIM was 85.3% and 59.7% based on the Beers criteria and the STOPP criteria. A total of 456 MRPs occurred in 247 patients. The most prevalent MRP categories were dosages that were too low and unnecessary medication therapies. Hyperpolypharmacy (taking ≥ 10 drugs) (odds ratio OR 3.736, 95% confidence interval CI 1.541–9.058, P = 0.004) and suffering from coronary heart disease (OR 2.620, 95%CI 1.090–6.297, P = 0.031) were the influencing factors of inappropriate prescribing (the presence of either PIM or MRP in a patient). Conclusion PIM and MRP were prevalent in older patients with chronic disease and polypharmacy in Chinese hospitals. More interventions are urgently needed to reduce PIM use and improve the quality of drug therapies. |
| first_indexed | 2024-04-10T19:40:50Z |
| format | Article |
| id | doaj.art-534e6547ff8e45acb3c38e8bd8ccee08 |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-04-10T19:40:50Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-534e6547ff8e45acb3c38e8bd8ccee082023-01-29T12:21:32ZengBMCBMC Geriatrics1471-23182023-01-0123111010.1186/s12877-023-03743-2A combination of Beers and STOPP criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy: a multicenter cross-sectional studyJing Tang0Ke Wang1Kun Yang2Dechun Jiang3Xianghua Fang4Su Su5Yang Lin6Shicai Chen7Hongyan Gu8Pengmei Li9Suying Yan10Department of Pharmacy, Xuanwu Hospital, the First Clinical Medical College of Capital Medical UniversityDepartment of Pharmacy, Xuanwu Hospital, the First Clinical Medical College of Capital Medical UniversityDepartment of Evidence-Based Medicine, Xuanwu Hospital, the First Clinical Medical College of Capital Medical UniversityDepartment of Pharmacy, Xuanwu Hospital, the First Clinical Medical College of Capital Medical UniversityDepartment of Evidence-Based Medicine, Xuanwu Hospital, the First Clinical Medical College of Capital Medical UniversityDepartment of Pharmacy, Xuanwu Hospital, the First Clinical Medical College of Capital Medical UniversityDepartment of Pharmacy, Beijing Anzhen Hospital Affiliated to Capital Medical UniversityDepartment of Pharmacy, Beijing Luhe Hospital Affiliated to Capital Medical UniversityDepartment of Pharmacy, Beijing Shijitan Hospital Affiliated to Capital Medical UniversityDepartment of Pharmacy, China-Japan Friendship HospitalDepartment of Pharmacy, Xuanwu Hospital, the First Clinical Medical College of Capital Medical UniversityAbstract Background Research on potentially inappropriate medications (PIM) and medication-related problems (MRP) among the Chinese population with chronic diseases and polypharmacy is insufficient. Objectives This study aimed to investigate the prevalence of PIM and MRP among older Chinese hospitalized patients with chronic diseases and polypharmacy and analyze the associated factors. Methods A retrospective cross-sectional study was conducted in five tertiary hospitals in Beijing. Patients aged ≥ 65 years with at least one chronic disease and taking at least five or more medications were included. Data were extracted from the hospitals’ electronic medical record systems. PIM was evaluated according to the 2015 Beers criteria and the 2014 Screening Tool of Older Persons’ Prescriptions (STOPP) criteria. MRPs were assessed and classified according to the Helper-Strand classification system. The prevalence of PIM and MRP and related factors were analyzed. Results A total of 852 cases were included. The prevalence of PIM was 85.3% and 59.7% based on the Beers criteria and the STOPP criteria. A total of 456 MRPs occurred in 247 patients. The most prevalent MRP categories were dosages that were too low and unnecessary medication therapies. Hyperpolypharmacy (taking ≥ 10 drugs) (odds ratio OR 3.736, 95% confidence interval CI 1.541–9.058, P = 0.004) and suffering from coronary heart disease (OR 2.620, 95%CI 1.090–6.297, P = 0.031) were the influencing factors of inappropriate prescribing (the presence of either PIM or MRP in a patient). Conclusion PIM and MRP were prevalent in older patients with chronic disease and polypharmacy in Chinese hospitals. More interventions are urgently needed to reduce PIM use and improve the quality of drug therapies.https://doi.org/10.1186/s12877-023-03743-2PolypharmacyInappropriate prescribingPotentially inappropriate medicationMedication related problemsAgedChronic disease |
| spellingShingle | Jing Tang Ke Wang Kun Yang Dechun Jiang Xianghua Fang Su Su Yang Lin Shicai Chen Hongyan Gu Pengmei Li Suying Yan A combination of Beers and STOPP criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy: a multicenter cross-sectional study BMC Geriatrics Polypharmacy Inappropriate prescribing Potentially inappropriate medication Medication related problems Aged Chronic disease |
| title | A combination of Beers and STOPP criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy: a multicenter cross-sectional study |
| title_full | A combination of Beers and STOPP criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy: a multicenter cross-sectional study |
| title_fullStr | A combination of Beers and STOPP criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy: a multicenter cross-sectional study |
| title_full_unstemmed | A combination of Beers and STOPP criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy: a multicenter cross-sectional study |
| title_short | A combination of Beers and STOPP criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy: a multicenter cross-sectional study |
| title_sort | combination of beers and stopp criteria better detects potentially inappropriate medications use among older hospitalized patients with chronic diseases and polypharmacy a multicenter cross sectional study |
| topic | Polypharmacy Inappropriate prescribing Potentially inappropriate medication Medication related problems Aged Chronic disease |
| url | https://doi.org/10.1186/s12877-023-03743-2 |
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