Combined effects of icam-1 single-nucleotide polymorphisms and environmental carcinogens on oral cancer susceptibility and clinicopathologic development.

Combined effects of icam-1 single-nucleotide polymorphisms and environmental carcinogens on oral cancer susceptibility and clinicopathologic development.

BACKGROUND: In Taiwan, oral cancer has causally been associated with environmental carcinogens. Intercellular adhesion molecule (ICAM)-1, a cell adhesion molecule with a key role in inflammation and immunosurveillance, was implicated in carcinogenesis by facilitating instability in the tumor environ...

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Main Authors: Chiao-Wen Lin, Chun-Yi Chuang, Chih-Hsin Tang, Junn-Liang Chang, Liang-Ming Lee, Wei-Jiunn Lee, Jyh-Ming Chow, Shun-Fa Yang, Ming-Hsien Chien
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3771971?pdf=render

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