The effectiveness and safety of one-stage iStent-based micro-invasive glaucoma surgery—A retrospective study
PurposeMicro-invasive glaucoma surgery involves a group of treatment methods associated with a low rate of side effects and good effectiveness outcomes. One of the most frequently performed procedures belonging to this group is iStent microstent implantation. The aim of this study was to perform a r...
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| Format: | Article |
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Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1273889/full |
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| author | Marta Hajduga-Szewczyk Marta Hajduga-Szewczyk Adrian Smedowski Adrian Smedowski Adrian Smedowski Iwona Filipecka Ewa Mrukwa-Kominek Ewa Mrukwa-Kominek |
| author_facet | Marta Hajduga-Szewczyk Marta Hajduga-Szewczyk Adrian Smedowski Adrian Smedowski Adrian Smedowski Iwona Filipecka Ewa Mrukwa-Kominek Ewa Mrukwa-Kominek |
| author_sort | Marta Hajduga-Szewczyk |
| collection | DOAJ |
| description | PurposeMicro-invasive glaucoma surgery involves a group of treatment methods associated with a low rate of side effects and good effectiveness outcomes. One of the most frequently performed procedures belonging to this group is iStent microstent implantation. The aim of this study was to perform a retrospective evaluation of the safety and efficacy of a combined procedure involving cataract phacoemulsification and single iStent microstent implantation, performed simultaneously.Materials and methodsThe complete medical records of 62 patients (91 eyes) were analyzed retrospectively, including the best corrected visual acuity, intraocular pressure, the mean defect of visual fields, and the number of active substances used in eye drops. The follow-up times were 1, 3, 6, 9, and 12 months after the surgical procedure.ResultsA significant improvement in the best corrected visual acuity and a reduction of the intraocular pressure were achieved after the surgery. On average, after 12 months, the best corrected visual acuity improved from 0.70 (0.25) to 0.91 (0.18; p = 0.001), the intraocular pressure reduced from 17.76 (3.95) to 14.91 (3.04; p = 0.0001), and the number of active substances used in eye drops reduced from 2.07 (1.08) to 0.70 (0.06; p = 0001). In addition, we found that patients who initially showed higher intraocular pressure values did not benefit from surgery in the aspect of the number of active substances used in their eye drops. Intraoperative and postoperative adverse events were transient and ultimately did not affect the outcomes.ConclusionSimultaneous cataract phacoemulsification with single iStent implantation in patients with open-angle glaucoma is a safe and effective method for reducing intraocular pressure and the number of topical medications that must be used. Having initially higher intraocular pressure values may limit the beneficial effects of iStent implantation by subordinating patients from topical treatment; thus, single iStent implantation may not be the most favorable choice in uncontrolled glaucoma cases. |
| first_indexed | 2024-03-10T03:49:12Z |
| format | Article |
| id | doaj.art-53539724a1ba47efaccee85689480152 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-03-10T03:49:12Z |
| publishDate | 2023-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-53539724a1ba47efaccee856894801522023-11-23T11:12:17ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-11-011010.3389/fmed.2023.12738891273889The effectiveness and safety of one-stage iStent-based micro-invasive glaucoma surgery—A retrospective studyMarta Hajduga-Szewczyk0Marta Hajduga-Szewczyk1Adrian Smedowski2Adrian Smedowski3Adrian Smedowski4Iwona Filipecka5Ewa Mrukwa-Kominek6Ewa Mrukwa-Kominek7Department of Ophthalmology, Professor K. Gibinski University Clinical Center, Medical University of Silesia, Katowice, PolandOkulus Plus Co, Bielsko-Biala, PolandDepartment of Ophthalmology, Professor K. Gibinski University Clinical Center, Medical University of Silesia, Katowice, PolandDepartment of Ophthalmology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, PolandGlaucoTech Co, Katowice, PolandOkulus Plus Co, Bielsko-Biala, PolandDepartment of Ophthalmology, Professor K. Gibinski University Clinical Center, Medical University of Silesia, Katowice, PolandDepartment of Ophthalmology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, PolandPurposeMicro-invasive glaucoma surgery involves a group of treatment methods associated with a low rate of side effects and good effectiveness outcomes. One of the most frequently performed procedures belonging to this group is iStent microstent implantation. The aim of this study was to perform a retrospective evaluation of the safety and efficacy of a combined procedure involving cataract phacoemulsification and single iStent microstent implantation, performed simultaneously.Materials and methodsThe complete medical records of 62 patients (91 eyes) were analyzed retrospectively, including the best corrected visual acuity, intraocular pressure, the mean defect of visual fields, and the number of active substances used in eye drops. The follow-up times were 1, 3, 6, 9, and 12 months after the surgical procedure.ResultsA significant improvement in the best corrected visual acuity and a reduction of the intraocular pressure were achieved after the surgery. On average, after 12 months, the best corrected visual acuity improved from 0.70 (0.25) to 0.91 (0.18; p = 0.001), the intraocular pressure reduced from 17.76 (3.95) to 14.91 (3.04; p = 0.0001), and the number of active substances used in eye drops reduced from 2.07 (1.08) to 0.70 (0.06; p = 0001). In addition, we found that patients who initially showed higher intraocular pressure values did not benefit from surgery in the aspect of the number of active substances used in their eye drops. Intraoperative and postoperative adverse events were transient and ultimately did not affect the outcomes.ConclusionSimultaneous cataract phacoemulsification with single iStent implantation in patients with open-angle glaucoma is a safe and effective method for reducing intraocular pressure and the number of topical medications that must be used. Having initially higher intraocular pressure values may limit the beneficial effects of iStent implantation by subordinating patients from topical treatment; thus, single iStent implantation may not be the most favorable choice in uncontrolled glaucoma cases.https://www.frontiersin.org/articles/10.3389/fmed.2023.1273889/fullglaucoma–surgeryiStentintra ocular pressurecataractsMIGS |
| spellingShingle | Marta Hajduga-Szewczyk Marta Hajduga-Szewczyk Adrian Smedowski Adrian Smedowski Adrian Smedowski Iwona Filipecka Ewa Mrukwa-Kominek Ewa Mrukwa-Kominek The effectiveness and safety of one-stage iStent-based micro-invasive glaucoma surgery—A retrospective study Frontiers in Medicine glaucoma–surgery iStent intra ocular pressure cataracts MIGS |
| title | The effectiveness and safety of one-stage iStent-based micro-invasive glaucoma surgery—A retrospective study |
| title_full | The effectiveness and safety of one-stage iStent-based micro-invasive glaucoma surgery—A retrospective study |
| title_fullStr | The effectiveness and safety of one-stage iStent-based micro-invasive glaucoma surgery—A retrospective study |
| title_full_unstemmed | The effectiveness and safety of one-stage iStent-based micro-invasive glaucoma surgery—A retrospective study |
| title_short | The effectiveness and safety of one-stage iStent-based micro-invasive glaucoma surgery—A retrospective study |
| title_sort | effectiveness and safety of one stage istent based micro invasive glaucoma surgery a retrospective study |
| topic | glaucoma–surgery iStent intra ocular pressure cataracts MIGS |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1273889/full |
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