Epigenetic Deregulation of MicroRNAs in Rhabdomyosarcoma and Neuroblastoma and Translational Perspectives

Epigenetic Deregulation of MicroRNAs in Rhabdomyosarcoma and Neuroblastoma and Translational Perspectives

Gene expression control mediated by microRNAs and epigenetic remodeling of chromatin are interconnected processes often involved in feedback regulatory loops, which strictly guide proper tissue differentiation during embryonal development. Altered expression of microRNAs is one of the mechanisms lea...

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Bibliographic Details
Main Authors: Paolo Romania, Alice Bertaina, Giorgia Bracaglia, Franco Locatelli, Doriana Fruci, Rossella Rota
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:International Journal of Molecular Sciences
Subjects:
microRNA
rhabdomyosarcoma
neuroblastoma
epigenetics
differentiation
Polycomb proteins
DNA methylation
histones
Online Access:http://www.mdpi.com/1422-0067/13/12/16554

Internet

http://www.mdpi.com/1422-0067/13/12/16554

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