Coexistence of anti‐MDA5 and anti‐PL‐7 in a patient with dermatomyositis: A case report

Abstract Coexisting anti‐MDA5 and anti‐PL‐7 antibodies are extremely rare. Anti‐MDA5 is associated with rapidly progressive interstitial lung disease (RP‐ILD), while anti‐PL‐7 is often associated with chronic or subacute ILD and better outcomes than RP‐ILD. We report a 41‐year‐old woman diagnosed wi...

Full description

Bibliographic Details
Main Authors: Hongyan Fu, Shaofeng Sun, Hong Zhang, Shuhong Chi, Weirong Ma, Guilan Yang, Juan Chen
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.6840
_version_ 1811162492588523520
author Hongyan Fu
Shaofeng Sun
Hong Zhang
Shuhong Chi
Weirong Ma
Guilan Yang
Juan Chen
author_facet Hongyan Fu
Shaofeng Sun
Hong Zhang
Shuhong Chi
Weirong Ma
Guilan Yang
Juan Chen
author_sort Hongyan Fu
collection DOAJ
description Abstract Coexisting anti‐MDA5 and anti‐PL‐7 antibodies are extremely rare. Anti‐MDA5 is associated with rapidly progressive interstitial lung disease (RP‐ILD), while anti‐PL‐7 is often associated with chronic or subacute ILD and better outcomes than RP‐ILD. We report a 41‐year‐old woman diagnosed with dermatomyositis (DM)‐associated ILD positive for anti‐MDA5 and anti‐PL‐7.
first_indexed 2024-04-10T06:30:41Z
format Article
id doaj.art-5354a36beee1405e90b59299dd056429
institution Directory Open Access Journal
issn 2050-0904
language English
last_indexed 2024-04-10T06:30:41Z
publishDate 2023-01-01
publisher Wiley
record_format Article
series Clinical Case Reports
spelling doaj.art-5354a36beee1405e90b59299dd0564292023-03-01T07:50:57ZengWileyClinical Case Reports2050-09042023-01-01111n/an/a10.1002/ccr3.6840Coexistence of anti‐MDA5 and anti‐PL‐7 in a patient with dermatomyositis: A case reportHongyan Fu0Shaofeng Sun1Hong Zhang2Shuhong Chi3Weirong Ma4Guilan Yang5Juan Chen6Department of Pulmonary and Critical Care Medicine General Hospital of Ningxia Medical University Yinchuan, Ningxia ChinaDepartment of Pulmonary and Critical Care Medicine General Hospital of Ningxia Medical University Yinchuan, Ningxia ChinaDepartment of Pulmonary and Critical Care Medicine General Hospital of Ningxia Medical University Yinchuan, Ningxia ChinaDepartment of Rheumatology General Hospital of Ningxia Medical University Yinchuan, Ningxia ChinaDepartment of Pulmonary and Critical Care Medicine General Hospital of Ningxia Medical University Yinchuan, Ningxia ChinaDepartment of Pulmonary and Critical Care Medicine General Hospital of Ningxia Medical University Yinchuan, Ningxia ChinaDepartment of Pulmonary and Critical Care Medicine General Hospital of Ningxia Medical University Yinchuan, Ningxia ChinaAbstract Coexisting anti‐MDA5 and anti‐PL‐7 antibodies are extremely rare. Anti‐MDA5 is associated with rapidly progressive interstitial lung disease (RP‐ILD), while anti‐PL‐7 is often associated with chronic or subacute ILD and better outcomes than RP‐ILD. We report a 41‐year‐old woman diagnosed with dermatomyositis (DM)‐associated ILD positive for anti‐MDA5 and anti‐PL‐7.https://doi.org/10.1002/ccr3.6840anti‐MDA5anti‐PL‐7dermatomyositisinterstitial lung diseasemyositis‐specific autoantibodies
spellingShingle Hongyan Fu
Shaofeng Sun
Hong Zhang
Shuhong Chi
Weirong Ma
Guilan Yang
Juan Chen
Coexistence of anti‐MDA5 and anti‐PL‐7 in a patient with dermatomyositis: A case report
Clinical Case Reports
anti‐MDA5
anti‐PL‐7
dermatomyositis
interstitial lung disease
myositis‐specific autoantibodies
title Coexistence of anti‐MDA5 and anti‐PL‐7 in a patient with dermatomyositis: A case report
title_full Coexistence of anti‐MDA5 and anti‐PL‐7 in a patient with dermatomyositis: A case report
title_fullStr Coexistence of anti‐MDA5 and anti‐PL‐7 in a patient with dermatomyositis: A case report
title_full_unstemmed Coexistence of anti‐MDA5 and anti‐PL‐7 in a patient with dermatomyositis: A case report
title_short Coexistence of anti‐MDA5 and anti‐PL‐7 in a patient with dermatomyositis: A case report
title_sort coexistence of anti mda5 and anti pl 7 in a patient with dermatomyositis a case report
topic anti‐MDA5
anti‐PL‐7
dermatomyositis
interstitial lung disease
myositis‐specific autoantibodies
url https://doi.org/10.1002/ccr3.6840
work_keys_str_mv AT hongyanfu coexistenceofantimda5andantipl7inapatientwithdermatomyositisacasereport
AT shaofengsun coexistenceofantimda5andantipl7inapatientwithdermatomyositisacasereport
AT hongzhang coexistenceofantimda5andantipl7inapatientwithdermatomyositisacasereport
AT shuhongchi coexistenceofantimda5andantipl7inapatientwithdermatomyositisacasereport
AT weirongma coexistenceofantimda5andantipl7inapatientwithdermatomyositisacasereport
AT guilanyang coexistenceofantimda5andantipl7inapatientwithdermatomyositisacasereport
AT juanchen coexistenceofantimda5andantipl7inapatientwithdermatomyositisacasereport