Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy
Abstract Cardiac sarcoidosis (CS) is a chameleon of cardiology, and it can mimic different cardiac diseases; among them is arrhythmogenic cardiomyopathy (ACM). We admitted a 70‐year‐old female patient with heart failure symptoms in 2015, who fulfilled all major ECG and non‐invasive imaging criteria...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-12-01
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| Series: | ESC Heart Failure |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ehf2.14123 |
| _version_ | 1797979235897311232 |
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| author | András Vereckei Gábor Katona Katalin Révész Hajnalka Vágó Veronika Müller Beáta Nagy Péter Nagy Róbert Sepp Kim Suvarna |
| author_facet | András Vereckei Gábor Katona Katalin Révész Hajnalka Vágó Veronika Müller Beáta Nagy Péter Nagy Róbert Sepp Kim Suvarna |
| author_sort | András Vereckei |
| collection | DOAJ |
| description | Abstract Cardiac sarcoidosis (CS) is a chameleon of cardiology, and it can mimic different cardiac diseases; among them is arrhythmogenic cardiomyopathy (ACM). We admitted a 70‐year‐old female patient with heart failure symptoms in 2015, who fulfilled all major ECG and non‐invasive imaging criteria of biventricular ACM. She was well with the recommended medications for 3 years, showing only isolated cardiac involvement, but in 2018, cervical and mediastinal lymphadenopathy appeared and cervical lymph node core biopsy histology, bronchoalveolar lavage flow cytometry strongly suggested extracardiac sarcoidosis. Therefore, our suspicion was that sarcoidosis is responsible for the cardiac involvement, which was not confirmed by PET‐CT and gallium scintigraphy examinations. At the end of 2018, she died in septicaemia with multiorgan failure, and only autopsy verified her CS. A new ECG algorithm published in 2021 for the differential diagnosis of CS and biventricular ACM, when applied on her ECGs recorded in 2015, suggested the diagnosis of CS. |
| first_indexed | 2024-04-11T05:35:44Z |
| format | Article |
| id | doaj.art-5358113879fb4ab6a0d67d4ddda2c17e |
| institution | Directory Open Access Journal |
| issn | 2055-5822 |
| language | English |
| last_indexed | 2024-04-11T05:35:44Z |
| publishDate | 2022-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | ESC Heart Failure |
| spelling | doaj.art-5358113879fb4ab6a0d67d4ddda2c17e2022-12-22T12:55:34ZengWileyESC Heart Failure2055-58222022-12-01964304431410.1002/ehf2.14123Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathyAndrás Vereckei0Gábor Katona1Katalin Révész2Hajnalka Vágó3Veronika Müller4Beáta Nagy5Péter Nagy6Róbert Sepp7Kim Suvarna8Department of Medicine and Hematology Semmelweis University Budapest HungaryDepartment of Medicine and Hematology Semmelweis University Budapest HungaryDepartment of Medicine and Hematology Semmelweis University Budapest HungaryHeart and Vascular Center Semmelweis University Budapest HungaryDepartment of Pulmonology Semmelweis University Budapest Hungary1st Department of Pathology and Experimental Cancer Research Semmelweis University Budapest Hungary1st Department of Pathology and Experimental Cancer Research Semmelweis University Budapest HungaryDepartment of Medicine, Division of Non‐Invasive Cardiology University of Szeged Szeged HungaryDepartment of Histopathology Sheffield Teaching Hospitals, NHS Foundation Trust, Northern General Hospital Sheffield UKAbstract Cardiac sarcoidosis (CS) is a chameleon of cardiology, and it can mimic different cardiac diseases; among them is arrhythmogenic cardiomyopathy (ACM). We admitted a 70‐year‐old female patient with heart failure symptoms in 2015, who fulfilled all major ECG and non‐invasive imaging criteria of biventricular ACM. She was well with the recommended medications for 3 years, showing only isolated cardiac involvement, but in 2018, cervical and mediastinal lymphadenopathy appeared and cervical lymph node core biopsy histology, bronchoalveolar lavage flow cytometry strongly suggested extracardiac sarcoidosis. Therefore, our suspicion was that sarcoidosis is responsible for the cardiac involvement, which was not confirmed by PET‐CT and gallium scintigraphy examinations. At the end of 2018, she died in septicaemia with multiorgan failure, and only autopsy verified her CS. A new ECG algorithm published in 2021 for the differential diagnosis of CS and biventricular ACM, when applied on her ECGs recorded in 2015, suggested the diagnosis of CS.https://doi.org/10.1002/ehf2.14123arrhythmogenic cardiomyopathyelectrocardiographyheart failuresarcoidosis |
| spellingShingle | András Vereckei Gábor Katona Katalin Révész Hajnalka Vágó Veronika Müller Beáta Nagy Péter Nagy Róbert Sepp Kim Suvarna Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy ESC Heart Failure arrhythmogenic cardiomyopathy electrocardiography heart failure sarcoidosis |
| title | Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy |
| title_full | Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy |
| title_fullStr | Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy |
| title_full_unstemmed | Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy |
| title_short | Cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy |
| title_sort | cardiac sarcoidosis completely mimicking biventricular arrhythmogenic cardiomyopathy |
| topic | arrhythmogenic cardiomyopathy electrocardiography heart failure sarcoidosis |
| url | https://doi.org/10.1002/ehf2.14123 |
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