Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage

Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage

Uridine metabolism is extensively reported to be involved in combating oxidative stress. Redox-imbalance-mediated ferroptosis plays a pivotal role in sepsis-induced acute lung injury (ALI). This study aims to explore the role of uridine metabolism in sepsis-induced ALI and the regulatory mechanism o...

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Bibliographic Details
Main Authors: Kai Lai, Congkuan Song, Minglang Gao, Yu Deng, Zilong Lu, Ning Li, Qing Geng
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
uridine
acute lung injury
ferroptosis
macrophage
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/24/6/5093

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