The Association Between Irritable Bowel Syndrome and Lactose Intolerance
Aim:Irritable bowel syndrome (IBS) and lactose intolerance (LI) may co-exist and readily cause diagnostic confusion due to similar symptomatology. This study aims to examine the frequency of LI in healthy controls and in participants diagnosed with IBS based on Roma III criteria, as an effort to inv...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayincilik
2019-12-01
|
| Series: | Namık Kemal Tıp Dergisi |
| Subjects: | |
| Online Access: |
http://namikkemalmedj.com/archives/archive-detail/article-preview/the-association-between-rritable-bowel-syndrome-an/40357
|
| _version_ | 1797921379728752640 |
|---|---|
| author | Mustafa Reşat DABAK Tuğba ARSLAN KÜÇÜK Sabah TÜZÜN Hüseyin ÇETİN Emel AHISHALI Can DOLAPÇIOĞLU |
| author_facet | Mustafa Reşat DABAK Tuğba ARSLAN KÜÇÜK Sabah TÜZÜN Hüseyin ÇETİN Emel AHISHALI Can DOLAPÇIOĞLU |
| author_sort | Mustafa Reşat DABAK |
| collection | DOAJ |
| description | Aim:Irritable bowel syndrome (IBS) and lactose intolerance (LI) may co-exist and readily cause diagnostic confusion due to similar symptomatology. This study aims to examine the frequency of LI in healthy controls and in participants diagnosed with IBS based on Roma III criteria, as an effort to investigate the association between IBS and LI.Materials and Methods:The patient population consisted of individuals between 18 and 80 years of age who attended between June-December 2013. Patients diagnosed with IBS based on Roma III criteria comprised the IBS group, and subtypes of IBS. Control group was healthy volunteers over 18 years of age with no IBS-like symptoms. All participants ingested 25 g of lactose dissolved in 250 ml of water within 5 minutes after 8 hours of fasting, in order to evaluate the LI via hydrogen breath test (0, 15, 30, 60, 90, and 120 minutes).Results:Of the total 200 participants, 100 (50%) were in the IBS group and 100 (50.0%) were in the control group. Of the total 70 patients (35.0%) with LI, 47 (47.0%) were in the IBS group and 23 (23.0%) were in the control group (p=0.001). Symptoms related to IBS were more common in participants with LI in both groups (p=0.001, p=0.001 respectively).Conclusion:A significantly increased frequency of LI was found among IBS patients than in controls. In addition, symptoms associated with lactose intake occurred at a higher frequency in IBS patient, although the difference was insignificant. |
| first_indexed | 2024-04-10T14:15:19Z |
| format | Article |
| id | doaj.art-535af896aa844002a7929726127f3278 |
| institution | Directory Open Access Journal |
| issn | 2587-0262 |
| language | English |
| last_indexed | 2024-04-10T14:15:19Z |
| publishDate | 2019-12-01 |
| publisher | Galenos Yayincilik |
| record_format | Article |
| series | Namık Kemal Tıp Dergisi |
| spelling | doaj.art-535af896aa844002a7929726127f32782023-02-15T16:09:33ZengGalenos YayincilikNamık Kemal Tıp Dergisi2587-02622019-12-017321722113049054The Association Between Irritable Bowel Syndrome and Lactose IntoleranceMustafa Reşat DABAK0Tuğba ARSLAN KÜÇÜK1Sabah TÜZÜN2Hüseyin ÇETİN3Emel AHISHALI4Can DOLAPÇIOĞLU5 Kartal Dr. Lütfi Kırdar Training and Research Hospital, Department of Family Medicine, İstanbul, TURKEY Kartal Dr. Lütfi Kırdar Training and Research Hospital, Department of Family Medicine, İstanbul, TURKEY Kartal Dr. Lütfi Kırdar Training and Research Hospital, Department of Family Medicine, İstanbul, TURKEY Kartal Dr. Lütfi Kırdar Training and Research Hospital, Department of Family Medicine, İstanbul, TURKEY Koç University Hospital, Department of Gastroenterology, İstanbul, TURKEY Kartal Dr. Lütfi Kırdar Training and Research Hospital, Department of Gastroenterology, İstanbul, TURKEY Aim:Irritable bowel syndrome (IBS) and lactose intolerance (LI) may co-exist and readily cause diagnostic confusion due to similar symptomatology. This study aims to examine the frequency of LI in healthy controls and in participants diagnosed with IBS based on Roma III criteria, as an effort to investigate the association between IBS and LI.Materials and Methods:The patient population consisted of individuals between 18 and 80 years of age who attended between June-December 2013. Patients diagnosed with IBS based on Roma III criteria comprised the IBS group, and subtypes of IBS. Control group was healthy volunteers over 18 years of age with no IBS-like symptoms. All participants ingested 25 g of lactose dissolved in 250 ml of water within 5 minutes after 8 hours of fasting, in order to evaluate the LI via hydrogen breath test (0, 15, 30, 60, 90, and 120 minutes).Results:Of the total 200 participants, 100 (50%) were in the IBS group and 100 (50.0%) were in the control group. Of the total 70 patients (35.0%) with LI, 47 (47.0%) were in the IBS group and 23 (23.0%) were in the control group (p=0.001). Symptoms related to IBS were more common in participants with LI in both groups (p=0.001, p=0.001 respectively).Conclusion:A significantly increased frequency of LI was found among IBS patients than in controls. In addition, symptoms associated with lactose intake occurred at a higher frequency in IBS patient, although the difference was insignificant. http://namikkemalmedj.com/archives/archive-detail/article-preview/the-association-between-rritable-bowel-syndrome-an/40357 irritable bowel syndromelactose intoleranceabdominal paindiarrhea |
| spellingShingle | Mustafa Reşat DABAK Tuğba ARSLAN KÜÇÜK Sabah TÜZÜN Hüseyin ÇETİN Emel AHISHALI Can DOLAPÇIOĞLU The Association Between Irritable Bowel Syndrome and Lactose Intolerance Namık Kemal Tıp Dergisi irritable bowel syndrome lactose intolerance abdominal pain diarrhea |
| title | The Association Between Irritable Bowel Syndrome and Lactose Intolerance |
| title_full | The Association Between Irritable Bowel Syndrome and Lactose Intolerance |
| title_fullStr | The Association Between Irritable Bowel Syndrome and Lactose Intolerance |
| title_full_unstemmed | The Association Between Irritable Bowel Syndrome and Lactose Intolerance |
| title_short | The Association Between Irritable Bowel Syndrome and Lactose Intolerance |
| title_sort | association between irritable bowel syndrome and lactose intolerance |
| topic | irritable bowel syndrome lactose intolerance abdominal pain diarrhea |
| url |
http://namikkemalmedj.com/archives/archive-detail/article-preview/the-association-between-rritable-bowel-syndrome-an/40357
|
| work_keys_str_mv | AT mustafaresatdabak theassociationbetweenirritablebowelsyndromeandlactoseintolerance AT tugbaarslankucuk theassociationbetweenirritablebowelsyndromeandlactoseintolerance AT sabahtuzun theassociationbetweenirritablebowelsyndromeandlactoseintolerance AT huseyincetin theassociationbetweenirritablebowelsyndromeandlactoseintolerance AT emelahishali theassociationbetweenirritablebowelsyndromeandlactoseintolerance AT candolapcioglu theassociationbetweenirritablebowelsyndromeandlactoseintolerance AT mustafaresatdabak associationbetweenirritablebowelsyndromeandlactoseintolerance AT tugbaarslankucuk associationbetweenirritablebowelsyndromeandlactoseintolerance AT sabahtuzun associationbetweenirritablebowelsyndromeandlactoseintolerance AT huseyincetin associationbetweenirritablebowelsyndromeandlactoseintolerance AT emelahishali associationbetweenirritablebowelsyndromeandlactoseintolerance AT candolapcioglu associationbetweenirritablebowelsyndromeandlactoseintolerance |