Twenty Years after Bovine Vaccinia in Brazil: Where We Are and Where Are We Going?
Orthopoxvirus (OPV) infections have been present in human life for hundreds of years. It is known that Variola virus (VARV) killed over 300 million people in the past; however, it had an end thanks to the physician Edward Jenner (who developed the first vaccine in history) and also thanks to a massi...
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| Format: | Article |
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MDPI AG
2021-03-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/10/4/406 |
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| author | Iago José da Silva Domingos Jaqueline Silva de Oliveira Kamila Lorene Soares Rocha Danilo Bretas de Oliveira Erna Geessien Kroon Galileu Barbosa Costa Giliane de Souza Trindade |
| author_facet | Iago José da Silva Domingos Jaqueline Silva de Oliveira Kamila Lorene Soares Rocha Danilo Bretas de Oliveira Erna Geessien Kroon Galileu Barbosa Costa Giliane de Souza Trindade |
| author_sort | Iago José da Silva Domingos |
| collection | DOAJ |
| description | Orthopoxvirus (OPV) infections have been present in human life for hundreds of years. It is known that Variola virus (VARV) killed over 300 million people in the past; however, it had an end thanks to the physician Edward Jenner (who developed the first vaccine in history) and also thanks to a massive vaccination program in the 20th century all over the world. Although the first vaccine was created using the Cowpox virus (CPXV), it turned out later that the Vaccinia virus was the one used during the vaccination program. VACV is the etiological agent of bovine vaccinia (BV), a zoonotic disease that has emerged in Brazil and South America in the last 20 years. BV has a great impact on local dairy economies and is also a burden to public health. In this review, we described the main events related to VACV and BV emergence in Brazil and South America, the increase of related scientific studies, and the issues that science, human and animal medicine are going to face if we do not be on guard to this virus and its disease. |
| first_indexed | 2024-03-10T12:44:24Z |
| format | Article |
| id | doaj.art-535c8ab3487b420a9dc2b086b2f56102 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T12:44:24Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-535c8ab3487b420a9dc2b086b2f561022023-11-21T13:33:50ZengMDPI AGPathogens2076-08172021-03-0110440610.3390/pathogens10040406Twenty Years after Bovine Vaccinia in Brazil: Where We Are and Where Are We Going?Iago José da Silva Domingos0Jaqueline Silva de Oliveira1Kamila Lorene Soares Rocha2Danilo Bretas de Oliveira3Erna Geessien Kroon4Galileu Barbosa Costa5Giliane de Souza Trindade6Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG 31270-901, BrazilLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG 31270-901, BrazilLaboratório de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, MG 39100-000, BrazilLaboratório de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, MG 39100-000, BrazilLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG 31270-901, BrazilDepartamento de Análise em Saúde e Vigilância de Doenças Não-Transmissíveis, Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, DF 70719-040, BrazilLaboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG 31270-901, BrazilOrthopoxvirus (OPV) infections have been present in human life for hundreds of years. It is known that Variola virus (VARV) killed over 300 million people in the past; however, it had an end thanks to the physician Edward Jenner (who developed the first vaccine in history) and also thanks to a massive vaccination program in the 20th century all over the world. Although the first vaccine was created using the Cowpox virus (CPXV), it turned out later that the Vaccinia virus was the one used during the vaccination program. VACV is the etiological agent of bovine vaccinia (BV), a zoonotic disease that has emerged in Brazil and South America in the last 20 years. BV has a great impact on local dairy economies and is also a burden to public health. In this review, we described the main events related to VACV and BV emergence in Brazil and South America, the increase of related scientific studies, and the issues that science, human and animal medicine are going to face if we do not be on guard to this virus and its disease.https://www.mdpi.com/2076-0817/10/4/406<i>Vaccinia virus</i>bovine vacciniapublic healthzoonosisneglected diseaselaboratory diagnosis |
| spellingShingle | Iago José da Silva Domingos Jaqueline Silva de Oliveira Kamila Lorene Soares Rocha Danilo Bretas de Oliveira Erna Geessien Kroon Galileu Barbosa Costa Giliane de Souza Trindade Twenty Years after Bovine Vaccinia in Brazil: Where We Are and Where Are We Going? Pathogens <i>Vaccinia virus</i> bovine vaccinia public health zoonosis neglected disease laboratory diagnosis |
| title | Twenty Years after Bovine Vaccinia in Brazil: Where We Are and Where Are We Going? |
| title_full | Twenty Years after Bovine Vaccinia in Brazil: Where We Are and Where Are We Going? |
| title_fullStr | Twenty Years after Bovine Vaccinia in Brazil: Where We Are and Where Are We Going? |
| title_full_unstemmed | Twenty Years after Bovine Vaccinia in Brazil: Where We Are and Where Are We Going? |
| title_short | Twenty Years after Bovine Vaccinia in Brazil: Where We Are and Where Are We Going? |
| title_sort | twenty years after bovine vaccinia in brazil where we are and where are we going |
| topic | <i>Vaccinia virus</i> bovine vaccinia public health zoonosis neglected disease laboratory diagnosis |
| url | https://www.mdpi.com/2076-0817/10/4/406 |
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