A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap.
Vascular endothelial growth factor (VEGF), through its activation of cell surface receptor tyrosine kinases including VEGFR1 and VEGFR2, is a vital regulator of stimulatory and inhibitory processes that keep angiogenesis--new capillary growth from existing microvasculature--at a dynamic balance in n...
Main Authors: | Florence T H Wu, Marianne O Stefanini, Feilim Mac Gabhann, Aleksander S Popel |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19352513/?tool=EBI |
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