Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes

Abstract Background The accuracy of using total keratometry (TK) value in recent IOL power calculation formulas in highly myopic eyes remained unknown. Methods Highly myopic patients who underwent uneventful cataract surgery were prospectively enrolled in this prospective comparative study. At one m...

Full description

Bibliographic Details
Main Authors: Ling Wei, Kaiwen Cheng, Wenwen He, Xiangjia Zhu, Yi Lu
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Eye and Vision
Subjects:
Online Access:https://doi.org/10.1186/s40662-022-00293-3
_version_ 1818253092130390016
author Ling Wei
Kaiwen Cheng
Wenwen He
Xiangjia Zhu
Yi Lu
author_facet Ling Wei
Kaiwen Cheng
Wenwen He
Xiangjia Zhu
Yi Lu
author_sort Ling Wei
collection DOAJ
description Abstract Background The accuracy of using total keratometry (TK) value in recent IOL power calculation formulas in highly myopic eyes remained unknown. Methods Highly myopic patients who underwent uneventful cataract surgery were prospectively enrolled in this prospective comparative study. At one month postoperatively, standard deviation (SD) of the prediction errors (PEs), mean and median absolute error (MedAE) of 103 highly myopic eyes were back-calculated and compared among ten formulas, including XGboost, RBF 3.0, Kane, Barrett Universal II, Emmetropia Verifying Optical 2.0, Cooke K6, Haigis, SRK/T, and Wang-Koch modifications of Haigis and SRK/T formulas, using either TK or standard keratometry (K) value. Results In highly myopic eyes, despite good agreement between TK and K (P > 0.05), larger differences between the two were associated with smaller central corneal thickness (P < 0.05). As to the refractive errors, TK method showed no differences compared to K method. The XGBoost, RBF 3.0 and Kane ranked top three when considering SDs of PEs. Using TK value, the XGboost calculator was comparable with the RBF 3.0 formula (P > 0.05), which both presented smaller MedAEs than others (all P < 0.05). As for the percentage of eyes within ± 0.50 D or ± 0.75 D of PE, the XGBoost TK showed comparable percentages with the RBF 3.0 TK formula (74.76% vs. 66.99%, or 90.29% vs. 87.38%, P > 0.05), and statistically larger percentages than the other eight formulas (P < 0.05). Conclusions Highly myopic eyes with thinner corneas tend to have larger differences between TK and K. The XGboost enhancement calculator and RBF 3.0 formula using TK showed the most promising outcomes in highly myopic eyes.
first_indexed 2024-12-12T16:34:34Z
format Article
id doaj.art-535fdd8aee3246f6bae858384d1ece8b
institution Directory Open Access Journal
issn 2326-0254
language English
last_indexed 2024-12-12T16:34:34Z
publishDate 2022-06-01
publisher BMC
record_format Article
series Eye and Vision
spelling doaj.art-535fdd8aee3246f6bae858384d1ece8b2022-12-22T00:18:41ZengBMCEye and Vision2326-02542022-06-01911910.1186/s40662-022-00293-3Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyesLing Wei0Kaiwen Cheng1Wenwen He2Xiangjia Zhu3Yi Lu4Department of Ophthalmology and Eye Institute, Eye and ENT Hospital of Fudan UniversityDepartment of Ophthalmology and Eye Institute, Eye and ENT Hospital of Fudan UniversityDepartment of Ophthalmology and Eye Institute, Eye and ENT Hospital of Fudan UniversityDepartment of Ophthalmology and Eye Institute, Eye and ENT Hospital of Fudan UniversityDepartment of Ophthalmology and Eye Institute, Eye and ENT Hospital of Fudan UniversityAbstract Background The accuracy of using total keratometry (TK) value in recent IOL power calculation formulas in highly myopic eyes remained unknown. Methods Highly myopic patients who underwent uneventful cataract surgery were prospectively enrolled in this prospective comparative study. At one month postoperatively, standard deviation (SD) of the prediction errors (PEs), mean and median absolute error (MedAE) of 103 highly myopic eyes were back-calculated and compared among ten formulas, including XGboost, RBF 3.0, Kane, Barrett Universal II, Emmetropia Verifying Optical 2.0, Cooke K6, Haigis, SRK/T, and Wang-Koch modifications of Haigis and SRK/T formulas, using either TK or standard keratometry (K) value. Results In highly myopic eyes, despite good agreement between TK and K (P > 0.05), larger differences between the two were associated with smaller central corneal thickness (P < 0.05). As to the refractive errors, TK method showed no differences compared to K method. The XGBoost, RBF 3.0 and Kane ranked top three when considering SDs of PEs. Using TK value, the XGboost calculator was comparable with the RBF 3.0 formula (P > 0.05), which both presented smaller MedAEs than others (all P < 0.05). As for the percentage of eyes within ± 0.50 D or ± 0.75 D of PE, the XGBoost TK showed comparable percentages with the RBF 3.0 TK formula (74.76% vs. 66.99%, or 90.29% vs. 87.38%, P > 0.05), and statistically larger percentages than the other eight formulas (P < 0.05). Conclusions Highly myopic eyes with thinner corneas tend to have larger differences between TK and K. The XGboost enhancement calculator and RBF 3.0 formula using TK showed the most promising outcomes in highly myopic eyes.https://doi.org/10.1186/s40662-022-00293-3High myopiaTotal keratometryCataract surgeryIOL power calculation
spellingShingle Ling Wei
Kaiwen Cheng
Wenwen He
Xiangjia Zhu
Yi Lu
Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes
Eye and Vision
High myopia
Total keratometry
Cataract surgery
IOL power calculation
title Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes
title_full Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes
title_fullStr Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes
title_full_unstemmed Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes
title_short Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes
title_sort application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes
topic High myopia
Total keratometry
Cataract surgery
IOL power calculation
url https://doi.org/10.1186/s40662-022-00293-3
work_keys_str_mv AT lingwei applicationoftotalkeratometryintenintraocularlenspowercalculationformulasinhighlymyopiceyes
AT kaiwencheng applicationoftotalkeratometryintenintraocularlenspowercalculationformulasinhighlymyopiceyes
AT wenwenhe applicationoftotalkeratometryintenintraocularlenspowercalculationformulasinhighlymyopiceyes
AT xiangjiazhu applicationoftotalkeratometryintenintraocularlenspowercalculationformulasinhighlymyopiceyes
AT yilu applicationoftotalkeratometryintenintraocularlenspowercalculationformulasinhighlymyopiceyes