Human Milk and Brain Development in Infants

Human milk is considered the most advantageous source of nourishment for infants. Even though there is no ideal composition of human milk, it still contains a unique combination of components that contribute to brain development. The aim of this review is to provide an overview on the possible corre...

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Main Authors: Martina Chiurazzi, Mauro Cozzolino, Tilman Reinelt, Thi Dao Nguyen, Stefanie Elke Chie, Giancarlo Natalucci, Maria Consolata Miletta
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Reproductive Medicine
Subjects:
Online Access:https://www.mdpi.com/2673-3897/2/2/11
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author Martina Chiurazzi
Mauro Cozzolino
Tilman Reinelt
Thi Dao Nguyen
Stefanie Elke Chie
Giancarlo Natalucci
Maria Consolata Miletta
author_facet Martina Chiurazzi
Mauro Cozzolino
Tilman Reinelt
Thi Dao Nguyen
Stefanie Elke Chie
Giancarlo Natalucci
Maria Consolata Miletta
author_sort Martina Chiurazzi
collection DOAJ
description Human milk is considered the most advantageous source of nourishment for infants. Even though there is no ideal composition of human milk, it still contains a unique combination of components that contribute to brain development. The aim of this review is to provide an overview on the possible correlation of human milk with the neurodevelopment of infants, with a special emphasis on myelination and epigenetic modifications. Research in human milk is a rapidly expanding field and cutting-edge technologies might contribute to identify specific mechanisms underlying the beneficial effects on human milk on neurodevelopment.
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spelling doaj.art-5365577c2d6f485f80324dc450d675932023-11-22T11:10:41ZengMDPI AGReproductive Medicine2673-38972021-06-012210711710.3390/reprodmed2020011Human Milk and Brain Development in InfantsMartina Chiurazzi0Mauro Cozzolino1Tilman Reinelt2Thi Dao Nguyen3Stefanie Elke Chie4Giancarlo Natalucci5Maria Consolata Miletta6Department of Clinical Medicine and Surgery, University of Naples “Federico II”, 80131 Naples, ItalyDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USALarsson-Rosenquist Centre for Neurodevelopment, Growth and Nutrition of the Newborn, Department of Neonatology, University Hospital Zurich and University of Zurich, 8006 Zurich, SwitzerlandLarsson-Rosenquist Centre for Neurodevelopment, Growth and Nutrition of the Newborn, Department of Neonatology, University Hospital Zurich and University of Zurich, 8006 Zurich, SwitzerlandLarsson-Rosenquist Centre for Neurodevelopment, Growth and Nutrition of the Newborn, Department of Neonatology, University Hospital Zurich and University of Zurich, 8006 Zurich, SwitzerlandLarsson-Rosenquist Centre for Neurodevelopment, Growth and Nutrition of the Newborn, Department of Neonatology, University Hospital Zurich and University of Zurich, 8006 Zurich, SwitzerlandLarsson-Rosenquist Centre for Neurodevelopment, Growth and Nutrition of the Newborn, Department of Neonatology, University Hospital Zurich and University of Zurich, 8006 Zurich, SwitzerlandHuman milk is considered the most advantageous source of nourishment for infants. Even though there is no ideal composition of human milk, it still contains a unique combination of components that contribute to brain development. The aim of this review is to provide an overview on the possible correlation of human milk with the neurodevelopment of infants, with a special emphasis on myelination and epigenetic modifications. Research in human milk is a rapidly expanding field and cutting-edge technologies might contribute to identify specific mechanisms underlying the beneficial effects on human milk on neurodevelopment.https://www.mdpi.com/2673-3897/2/2/11human milkneurodevelopmentmacronutrientssialic acidmicronutrientsbioactive components
spellingShingle Martina Chiurazzi
Mauro Cozzolino
Tilman Reinelt
Thi Dao Nguyen
Stefanie Elke Chie
Giancarlo Natalucci
Maria Consolata Miletta
Human Milk and Brain Development in Infants
Reproductive Medicine
human milk
neurodevelopment
macronutrients
sialic acid
micronutrients
bioactive components
title Human Milk and Brain Development in Infants
title_full Human Milk and Brain Development in Infants
title_fullStr Human Milk and Brain Development in Infants
title_full_unstemmed Human Milk and Brain Development in Infants
title_short Human Milk and Brain Development in Infants
title_sort human milk and brain development in infants
topic human milk
neurodevelopment
macronutrients
sialic acid
micronutrients
bioactive components
url https://www.mdpi.com/2673-3897/2/2/11
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AT tilmanreinelt humanmilkandbraindevelopmentininfants
AT thidaonguyen humanmilkandbraindevelopmentininfants
AT stefanieelkechie humanmilkandbraindevelopmentininfants
AT giancarlonatalucci humanmilkandbraindevelopmentininfants
AT mariaconsolatamiletta humanmilkandbraindevelopmentininfants