Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection.

Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection.

Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea and pseudomembranous colitis in the USA. In addition to these symptoms, patients with CDI can develop severe inflammation and tissue damage, resulting in life-threatening toxic megacolon. CDI is mediated by two larg...

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Bibliographic Details
Main Authors:	F Christopher Peritore-Galve, John A Shupe, Rory J Cave, Kevin O Childress, M Kay Washington, Sarah A Kuehne, D Borden Lacy
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2022-02-01
Series:	PLoS Pathogens
Online Access:	https://doi.org/10.1371/journal.ppat.1010323

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