Poly(9<i>H</i>-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors
Organic semiconductors and conducting polymers are the most promising next-generation conducting materials for electrochemical biosensors as the greener and cheaper alternative for electrodes based on transition metals or their oxides. Therefore, polycarbazole as the organic semiconducting polymer w...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-08-01
|
| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/10/9/104 |
| _version_ | 1797556089629179904 |
|---|---|
| author | Gintautas Bagdžiūnas Delianas Palinauskas |
| author_facet | Gintautas Bagdžiūnas Delianas Palinauskas |
| author_sort | Gintautas Bagdžiūnas |
| collection | DOAJ |
| description | Organic semiconductors and conducting polymers are the most promising next-generation conducting materials for electrochemical biosensors as the greener and cheaper alternative for electrodes based on transition metals or their oxides. Therefore, polycarbazole as the organic semiconducting polymer was electrochemically synthesized and deposited on working electrode. Structure and semiconducting properties of polycarbazole have theoretically and experimentally been analyzed and proved. For these electrochemical systems, a maximal sensitivity of 14 μA·cm<sup>−2</sup>·mM<sup>−1</sup>, a wide linear range of detection up to 5 mM, and a minimal limit of detection of around 0.2 mM were achieved. Moreover, Michaelis’s constant of these sensors depends not only on the enzyme but on the material of electrode and applied potential. The electrocatalytic mechanism and performance of the non- and enzymatic sensors based on this material as a conducting layer have been discussed by estimating pseudocapacitive and faradaic currents and by adding glucose as an analyte at the different applied potentials. In this work, the attention was focused on the electrochemical origin and mechanism involved in the non- and enzymatic oxidation and reduction of glucose. |
| first_indexed | 2024-03-10T16:56:45Z |
| format | Article |
| id | doaj.art-53698334d6bd4b379ff0d900f4de80bf |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-10T16:56:45Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-53698334d6bd4b379ff0d900f4de80bf2023-11-20T11:06:09ZengMDPI AGBiosensors2079-63742020-08-0110910410.3390/bios10090104Poly(9<i>H</i>-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose SensorsGintautas Bagdžiūnas0Delianas Palinauskas1Institute of Biochemistry, Life Sciences Centre, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, LithuaniaInstitute of Biochemistry, Life Sciences Centre, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, LithuaniaOrganic semiconductors and conducting polymers are the most promising next-generation conducting materials for electrochemical biosensors as the greener and cheaper alternative for electrodes based on transition metals or their oxides. Therefore, polycarbazole as the organic semiconducting polymer was electrochemically synthesized and deposited on working electrode. Structure and semiconducting properties of polycarbazole have theoretically and experimentally been analyzed and proved. For these electrochemical systems, a maximal sensitivity of 14 μA·cm<sup>−2</sup>·mM<sup>−1</sup>, a wide linear range of detection up to 5 mM, and a minimal limit of detection of around 0.2 mM were achieved. Moreover, Michaelis’s constant of these sensors depends not only on the enzyme but on the material of electrode and applied potential. The electrocatalytic mechanism and performance of the non- and enzymatic sensors based on this material as a conducting layer have been discussed by estimating pseudocapacitive and faradaic currents and by adding glucose as an analyte at the different applied potentials. In this work, the attention was focused on the electrochemical origin and mechanism involved in the non- and enzymatic oxidation and reduction of glucose.https://www.mdpi.com/2079-6374/10/9/104Polycarbazoleglucose sensorglucose oxidaseorganic semiconductornon-enzymatic sensors |
| spellingShingle | Gintautas Bagdžiūnas Delianas Palinauskas Poly(9<i>H</i>-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors Biosensors Polycarbazole glucose sensor glucose oxidase organic semiconductor non-enzymatic sensors |
| title | Poly(9<i>H</i>-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors |
| title_full | Poly(9<i>H</i>-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors |
| title_fullStr | Poly(9<i>H</i>-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors |
| title_full_unstemmed | Poly(9<i>H</i>-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors |
| title_short | Poly(9<i>H</i>-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors |
| title_sort | poly 9 i h i carbazole as a organic semiconductor for enzymatic and non enzymatic glucose sensors |
| topic | Polycarbazole glucose sensor glucose oxidase organic semiconductor non-enzymatic sensors |
| url | https://www.mdpi.com/2079-6374/10/9/104 |
| work_keys_str_mv | AT gintautasbagdziunas poly9ihicarbazoleasaorganicsemiconductorforenzymaticandnonenzymaticglucosesensors AT delianaspalinauskas poly9ihicarbazoleasaorganicsemiconductorforenzymaticandnonenzymaticglucosesensors |