Streptococcus oralis Employs Multiple Mechanisms of Salivary Mucin Binding That Differ Between Strains

Streptococcus oralis Employs Multiple Mechanisms of Salivary Mucin Binding That Differ Between Strains

Streptococcus oralis is an oral commensal and opportunistic pathogen that can enter the bloodstream and cause bacteremia and infective endocarditis. Here, we investigated the mechanisms of S. oralis binding to oral mucins using clinical isolates, isogenic mutants and glycoconjugates. S. oralis bound...

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Bibliographic Details
Main Authors: Gurdeep Chahal, Macarena P. Quintana-Hayashi, Meztlli O. Gaytán, John Benktander, Medea Padra, Samantha J. King, Sara K. Linden
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
glycosylation
Lewis antigen
sialylation
salivary mucins
adhesin
sortase
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.889711/full

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