Crocin improves the renal autophagy in rat experimental membranous nephropathy via regulating the SIRT1/Nrf2/HO-1 signaling pathway

Crocin improves the renal autophagy in rat experimental membranous nephropathy via regulating the SIRT1/Nrf2/HO-1 signaling pathway

AbstractMembranous nephropathy (MN) is a glomerular disease. Crocin is isolated from saffron and gardenia. Its antioxidant, anti-inflammatory, anti-hyperlipidemic, anti-atherosclerotic, anti-tumor, free-radical scavenging and neuroprotective activities have been well established. We investigated the...

Full description

Bibliographic Details
Main Authors:	Hongyan Liu, Hong Cheng, Hongyun Wang, Qiong Wang, Jun Yuan
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Series:	Renal Failure
Subjects:	Membranous nephropathy crocin passive Heymann nephritis proteinuria podocyte Sirt1/Nrf2/HO-1 pathways
Online Access:	https://www.tandfonline.com/doi/10.1080/0886022X.2023.2253924

Similar Items

Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway
by: Xiaowan Wang, et al.
Published: (2021-11-01)

Corrigendum: Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway
by: Xiaowan Wang, et al.
Published: (2022-04-01)

Membranous nephropathy: Clearer pathology and mechanisms identify potential strategies for treatment
by: Edmund Y. M. Chung, et al.
Published: (2022-11-01)

Metalloporphyrins Reduce Proteinuria in Podocyte Immune Injury: The Role of Metal and Porphyrin Moieties
by: Elias A. Lianos, et al.
Published: (2023-08-01)

Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways
by: Vahid Radmehr, et al.
Published: (2022-11-01)

Pterostilbene suppresses oxidative stress and allergic airway inflammation through AMPK/Sirt1 and Nrf2/HO‐1 pathways
by: Chang Xu, et al.
Published: (2021-12-01)

Ferroptosis is involved in passive Heymann nephritis in rats
by: Xiujie Shi, et al.
Published: (2023-10-01)

Lycopene alleviates oxidative stress-induced cell injury in human vascular endothelial cells by encouraging the SIRT1/Nrf2/HO-1 pathway
by: Wenhai Guo, et al.
Published: (2023-12-01)

Crocin Protects Podocytes Against Oxidative Stress and Inflammation Induced by High Glucose Through Inhibition of NF-κB
by: Sutong Li, et al.
Published: (2017-07-01)

Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO‐1 pathway
by: Qi Huang, et al.
Published: (2021-08-01)

Olmesartan Prevents Microalbuminuria in db/db Diabetic Mice Through Inhibition of Angiotensin II/p38/SIRT1-Induced Podocyte Apoptosis
by: Junhui Gu, et al.
Published: (2016-11-01)

MORPHOFUNCTIONAL STATEOFKIDNEYS OF RATSAFTER INJECTIONOFPLACENTAL CRYOEXTRACT IN HEYMANN NEPHRITIS
by: I.I. Kondakov, et al.
Published: (2017-02-01)

Idiopathic membranous nephropathy: Evolution in understanding the problem
by: I N Bobkova, et al.
Published: (2016-06-01)

Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways
by: Ahmed L. Alaofi
Published: (2020-07-01)

tBHQ attenuates podocyte injury in diabetic nephropathy by inhibiting NADPH oxidase-derived ROS generation via the Nrf2/HO-1 signalling pathway
by: Ting Liu, et al.
Published: (2022-09-01)

ATF4-dependent heme-oxygenase-1 attenuates diabetic nephropathy by inducing autophagy and inhibiting apoptosis in podocyte
by: Shizhu Yuan, et al.
Published: (2021-01-01)

Yishen capsule promotes podocyte autophagy through regulating SIRT1/NF-κB signaling pathway to improve diabetic nephropathy
by: Yuxiang Liu, et al.
Published: (2021-01-01)

SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway
by: Xiaodan Sun, et al.
Published: (2019-08-01)

Apigenin-Loaded Solid Lipid Nanoparticle Attenuates Diabetic Nephropathy Induced by Streptozotocin Nicotinamide Through Nrf2/HO-1/NF-kB Signalling Pathway
by: Li P, et al.
Published: (2020-11-01)

Evolution in the understanding of idiopathic membranous nephropathy pathogenesis: from experimental models to the clinic
by: I. N. Bobkova, et al.
Published: (2018-01-01)

Apigenin-Loaded Solid Lipid Nanoparticle Attenuates Diabetic Nephropathy Induced by Streptozotocin Nicotinamide Through Nrf2/HO-1/NF-kB Signalling Pathway [Retraction]
by: Li P, et al.
Published: (2022-08-01)

Baicalein ameliorates pristane-induced lupus nephritis via activating Nrf2/HO-1 in myeloid-derived suppressor cells
by: Dan Li, et al.
Published: (2019-04-01)

Podocyte injury of diabetic nephropathy: Novel mechanism discovery and therapeutic prospects
by: Xiandeng Li, et al.
Published: (2023-12-01)

suPAR and WT1 modify the adhesion of podocytes and are related to proteinuria in class IV lupus nephritis
by: Juan-José Bollain-y-Goytia, et al.
Published: (2023-12-01)

Podocyte Pathology and Nephropathy
by: Barbara eLewko, et al.
Published: (2015-09-01)

Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1
by: Lei Zhang, et al.
Published: (2018-05-01)

Antioxidant Effects of Statins by Modulating Nrf2 and Nrf2/HO-1 Signaling in Different Diseases
by: Atena Mansouri, et al.
Published: (2022-02-01)

Yi Shen An, a Chinese traditional prescription, ameliorates membranous glomerulonephritis induced by cationic bovine serum albumin in rats
by: Yun-Li Zhao, et al.
Published: (2022-12-01)

Value of immunohistochemical expression of podocalyxin in active lupus nephritis
by: Maha Abdelmoneim Behairy, et al.
Published: (2018-01-01)

Value of immunohistochemical expression of podocalyxin in active lupus nephritis
by: Maha Abdelmoneim Behairy, et al.
Published: (2018-01-01)

TangShenWeiNing Formula Prevents Diabetic Nephropathy by Protecting Podocytes Through the SIRT1/HIF-1α Pathway
by: Jing Chang, et al.
Published: (2022-05-01)

Formononetin Activates the Nrf2/ARE Signaling Pathway Via Sirt1 to Improve Diabetic Renal Fibrosis
by: Kai Zhuang, et al.
Published: (2021-01-01)

Antioxidant and anti-inflammatory activities of Centratherum anthelminticum (L.) Kuntze seed oil in diabetic nephropathy via modulation of Nrf-2/HO-1 and NF-κB pathway
by: Nida Baig, et al.
Published: (2022-11-01)

Daphnetin Attenuated Cisplatin-Induced Acute Nephrotoxicity With Enhancing Antitumor Activity of Cisplatin by Upregulating SIRT1/SIRT6-Nrf2 Pathway
by: Xiaoye Fan, et al.
Published: (2020-12-01)

Short ELF-EMF Exposure Targets SIRT1/Nrf2/HO-1 Signaling in THP-1 Cells
by: Antonia Patruno, et al.
Published: (2020-10-01)

Anti-Fibrotic Effect of Losartan, an Angiotensin II Receptor Blocker, Is Mediated through Inhibition of ER Stress via Up-Regulation of SIRT1, Followed by Induction of HO-1 and Thioredoxin
by: Hyosang Kim, et al.
Published: (2017-01-01)

Lycopene attenuates chlorpyrifos-induced hepatotoxicity in rats via activation of Nrf2/HO-1 axis
by: Ashraf B. Abdel-Naim, et al.
Published: (2023-09-01)

The Modified Vaccination Technique
by: Arpad Barabas, et al.
Published: (2018-12-01)

Activation of the Nrf2-ARE Pathway Ameliorates Hyperglycemia-Mediated Mitochondrial Dysfunction in Podocytes Partly Through Sirt1
by: Qunzi Zhang, et al.
Published: (2018-07-01)

Eletrophilic Chemistry of Tranilast Is Involved in Its Anti-Colitic Activity via Nrf2-HO-1 Pathway Activation
by: Seongkeun Jeong, et al.
Published: (2021-10-01)