Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational study
Abstract Background and purpose The complications of radical surgery for cervical cancer can increase patient suffering and affect their quality of life. This retrospective study assessed the safety of radical hysterectomy (RH) with pelvic lymph node dissection (PLND) by observing the complications...
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | BMC Cancer |
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| Online Access: | https://doi.org/10.1186/s12885-022-10395-9 |
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| author | Huang Jing Wu Xiuhong Yu Ying Cheng Xiyun Luo Deping Shen Changmei Wang Qi Peng Tao Pan Yiyun |
| author_facet | Huang Jing Wu Xiuhong Yu Ying Cheng Xiyun Luo Deping Shen Changmei Wang Qi Peng Tao Pan Yiyun |
| author_sort | Huang Jing |
| collection | DOAJ |
| description | Abstract Background and purpose The complications of radical surgery for cervical cancer can increase patient suffering and affect their quality of life. This retrospective study assessed the safety of radical hysterectomy (RH) with pelvic lymph node dissection (PLND) by observing the complications of patients with cervical cancer who underwent this procedure in a single centre over 10 years. Our findings may provide experience and evidence for preventing and reducing complications. Methods A total of 2226 cervical cancer patients who met the inclusion criteria were enrolled. All patients underwent RH + PLND. Intraoperative injury to adjacent tissues and short-term and long-term complications were recorded to analyze factors associated with the occurrence of complications. Results Postoperative complications occurred in 34.41% (766/2226) of patients, including 7.68% of patients with injury to adjacent tissues, 31.45% with short-term complications, and 2.96% with long-term complications. Age, tumor size, invasion depth, parametrial invasion, lymph vascular space invasion (LVSI), lymph node metastasis, International Federation of Gynaecology and Obstetrics (FIGO) stage, and surgical procedure were closely associated with the postoperative complications of RH + PLND (P < 0.05). Conclusions The results of this study showed that RH + PLND for cervical cancer is safe and practical. Patients aged 40–60 years, with tumors ≥ 4 cm, invasion depth ≥ 2/3, parametrial invasion, LVSI, lymph node metastasis, FIGO stage > IB2, and who underwent open surgery were more prone to complications. |
| first_indexed | 2024-04-12T02:59:26Z |
| format | Article |
| id | doaj.art-536e777d6017451b9d1dec01094acb75 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-04-12T02:59:26Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-536e777d6017451b9d1dec01094acb752022-12-22T03:50:42ZengBMCBMC Cancer1471-24072022-12-012211910.1186/s12885-022-10395-9Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational studyHuang Jing0Wu Xiuhong1Yu Ying2Cheng Xiyun3Luo Deping4Shen Changmei5Wang Qi6Peng Tao7Pan Yiyun8Department of Gynecology and Oncology, Ganzhou Cancer HospitalRadiotherapy Center, Ganzhou Cancer HospitalDepartment of Gynecology and Oncology, Ganzhou Cancer HospitalDepartment of Gynecology and Oncology, Ganzhou Cancer HospitalDepartment of Gynecology and Oncology, Ganzhou Cancer HospitalDepartment of Gynecology and Oncology, Ganzhou Cancer HospitalDepartment of Gynecology and Oncology, Ganzhou Cancer HospitalDepartment of Gynecology and Oncology, Ganzhou Cancer HospitalChemotherapy Center, Ganzhou Cancer HospitalAbstract Background and purpose The complications of radical surgery for cervical cancer can increase patient suffering and affect their quality of life. This retrospective study assessed the safety of radical hysterectomy (RH) with pelvic lymph node dissection (PLND) by observing the complications of patients with cervical cancer who underwent this procedure in a single centre over 10 years. Our findings may provide experience and evidence for preventing and reducing complications. Methods A total of 2226 cervical cancer patients who met the inclusion criteria were enrolled. All patients underwent RH + PLND. Intraoperative injury to adjacent tissues and short-term and long-term complications were recorded to analyze factors associated with the occurrence of complications. Results Postoperative complications occurred in 34.41% (766/2226) of patients, including 7.68% of patients with injury to adjacent tissues, 31.45% with short-term complications, and 2.96% with long-term complications. Age, tumor size, invasion depth, parametrial invasion, lymph vascular space invasion (LVSI), lymph node metastasis, International Federation of Gynaecology and Obstetrics (FIGO) stage, and surgical procedure were closely associated with the postoperative complications of RH + PLND (P < 0.05). Conclusions The results of this study showed that RH + PLND for cervical cancer is safe and practical. Patients aged 40–60 years, with tumors ≥ 4 cm, invasion depth ≥ 2/3, parametrial invasion, LVSI, lymph node metastasis, FIGO stage > IB2, and who underwent open surgery were more prone to complications.https://doi.org/10.1186/s12885-022-10395-9Cervical cancerRadical hysterectomyPelvic lymph node dissectionComplicationsClinical observation |
| spellingShingle | Huang Jing Wu Xiuhong Yu Ying Cheng Xiyun Luo Deping Shen Changmei Wang Qi Peng Tao Pan Yiyun Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational study BMC Cancer Cervical cancer Radical hysterectomy Pelvic lymph node dissection Complications Clinical observation |
| title | Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational study |
| title_full | Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational study |
| title_fullStr | Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational study |
| title_full_unstemmed | Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational study |
| title_short | Complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer: a 10-year single-centre clinical observational study |
| title_sort | complications of radical hysterectomy with pelvic lymph node dissection for cervical cancer a 10 year single centre clinical observational study |
| topic | Cervical cancer Radical hysterectomy Pelvic lymph node dissection Complications Clinical observation |
| url | https://doi.org/10.1186/s12885-022-10395-9 |
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