The Toronto Concussion Study: a prospective investigation of characteristics in a cohort of adults from the general population seeking care following acute concussion, 2016–2020
PurposeThere is limited research regarding the characteristics of those from the general population who seek care following acute concussion.MethodsTo address this gap, a large cohort of 473 adults diagnosed with an acute concussion (female participants = 287; male participants = 186) was followed u...
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| Format: | Article |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1152504/full |
| _version_ | 1797741324136349696 |
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| author | Paul Comper Paul Comper Paul Comper Evan Foster Tharshini Chandra Laura Langer Catherine Wiseman-Hakes Catherine Wiseman-Hakes George Mochizuki George Mochizuki Lesley Ruttan Lesley Ruttan David W. Lawrence David W. Lawrence David W. Lawrence Elizabeth L. Inness Elizabeth L. Inness Elizabeth L. Inness Jonathan Gladstone Jonathan Gladstone Jonathan Gladstone Cristina Saverino Alan Tam Alan Tam Alice Kam Alice Kam Alice Kam Alice Kam Firas Al-Rawi Firas Al-Rawi Firas Al-Rawi Mark Theodore Bayley Mark Theodore Bayley |
| author_facet | Paul Comper Paul Comper Paul Comper Evan Foster Tharshini Chandra Laura Langer Catherine Wiseman-Hakes Catherine Wiseman-Hakes George Mochizuki George Mochizuki Lesley Ruttan Lesley Ruttan David W. Lawrence David W. Lawrence David W. Lawrence Elizabeth L. Inness Elizabeth L. Inness Elizabeth L. Inness Jonathan Gladstone Jonathan Gladstone Jonathan Gladstone Cristina Saverino Alan Tam Alan Tam Alice Kam Alice Kam Alice Kam Alice Kam Firas Al-Rawi Firas Al-Rawi Firas Al-Rawi Mark Theodore Bayley Mark Theodore Bayley |
| author_sort | Paul Comper |
| collection | DOAJ |
| description | PurposeThere is limited research regarding the characteristics of those from the general population who seek care following acute concussion.MethodsTo address this gap, a large cohort of 473 adults diagnosed with an acute concussion (female participants = 287; male participants = 186) was followed using objective measures prospectively over 16 weeks beginning at a mean of 5.1 days post-injury.ResultsFalls were the most common mechanism of injury (MOI) (n = 137, 29.0%), followed by sports-related recreation (n = 119, 25.2%). Male participants were more likely to be injured playing recreational sports or in a violence-related incident; female participants were more likely to be injured by falling. Post-traumatic amnesia (PTA) was reported by 80 participants (16.9 %), and loss of consciousness (LOC) was reported by 110 (23.3%). In total, 54 participants (11.4%) reported both PTA and LOC. Male participants had significantly higher rates of PTA and LOC after their injury compared to their female counterparts. Higher initial symptom burden was associated with a longer duration of recovery for both male and female participants. Female participants had more symptoms and higher severity of symptoms at presentation compared to male participants. Female participants were identified to have a longer recovery duration, with a mean survival time of 6.50 weeks compared to 5.45 weeks in male participants (p < 0.0001). A relatively high proportion of female and male participants in this study reported premorbid diagnoses of depression and anxiety compared to general population characteristics.ConclusionAlthough premorbid diagnoses of depression and/or anxiety were associated with higher symptom burden at the initial visit, the duration of symptoms was not directly associated with a pre-injury history of psychological/psychiatric disturbance. This cohort of adults, from the general population, seeking care for their acute concussion attained clinical and functional recovery over a period of 4–12 weeks. |
| first_indexed | 2024-03-12T14:25:10Z |
| format | Article |
| id | doaj.art-536f9003434c4941b8eef2752ec1d15e |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-03-12T14:25:10Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-536f9003434c4941b8eef2752ec1d15e2023-08-18T07:40:40ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-08-011410.3389/fneur.2023.11525041152504The Toronto Concussion Study: a prospective investigation of characteristics in a cohort of adults from the general population seeking care following acute concussion, 2016–2020Paul Comper0Paul Comper1Paul Comper2Evan Foster3Tharshini Chandra4Laura Langer5Catherine Wiseman-Hakes6Catherine Wiseman-Hakes7George Mochizuki8George Mochizuki9Lesley Ruttan10Lesley Ruttan11David W. Lawrence12David W. Lawrence13David W. Lawrence14Elizabeth L. Inness15Elizabeth L. Inness16Elizabeth L. Inness17Jonathan Gladstone18Jonathan Gladstone19Jonathan Gladstone20Cristina Saverino21Alan Tam22Alan Tam23Alice Kam24Alice Kam25Alice Kam26Alice Kam27Firas Al-Rawi28Firas Al-Rawi29Firas Al-Rawi30Mark Theodore Bayley31Mark Theodore Bayley32Toronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaFaculty of Medicine, Rehabilitation Sciences Institute, University of Toronto, Toronto, ON, CanadaFaculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaSchool of Rehabilitation Science, McMaster University, Hamilton, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaSchool of Kinesiology and Health Science, York University, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaGraduate Department of Psychological Clinical Science, University of Toronto Scarborough, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaFaculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, CanadaDepartment of Family and Community Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaFaculty of Medicine, Rehabilitation Sciences Institute, University of Toronto, Toronto, ON, CanadaDepartment of Physical Therapy, University of Toronto, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, CanadaDivision of Neurology, Department of Pediatrics, Hospital for Sick Children, Toronto, ON, Canada0Gladstone Headache Clinic, Toronto, ON, Canada1Toronto Western Hospital, University Health Network, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada2Division of Physiatry, Department of Medicine, University of Toronto, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada1Toronto Western Hospital, University Health Network, Toronto, ON, Canada2Division of Physiatry, Department of Medicine, University of Toronto, Toronto, ON, Canada3North York General Hospital, Toronto, ON, Canada1Toronto Western Hospital, University Health Network, Toronto, ON, Canada4Toronto General Hospital, University Health Network, Toronto, ON, Canada5Faculty of Medicine, University of Toronto, Toronto, ON, CanadaToronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada2Division of Physiatry, Department of Medicine, University of Toronto, Toronto, ON, CanadaPurposeThere is limited research regarding the characteristics of those from the general population who seek care following acute concussion.MethodsTo address this gap, a large cohort of 473 adults diagnosed with an acute concussion (female participants = 287; male participants = 186) was followed using objective measures prospectively over 16 weeks beginning at a mean of 5.1 days post-injury.ResultsFalls were the most common mechanism of injury (MOI) (n = 137, 29.0%), followed by sports-related recreation (n = 119, 25.2%). Male participants were more likely to be injured playing recreational sports or in a violence-related incident; female participants were more likely to be injured by falling. Post-traumatic amnesia (PTA) was reported by 80 participants (16.9 %), and loss of consciousness (LOC) was reported by 110 (23.3%). In total, 54 participants (11.4%) reported both PTA and LOC. Male participants had significantly higher rates of PTA and LOC after their injury compared to their female counterparts. Higher initial symptom burden was associated with a longer duration of recovery for both male and female participants. Female participants had more symptoms and higher severity of symptoms at presentation compared to male participants. Female participants were identified to have a longer recovery duration, with a mean survival time of 6.50 weeks compared to 5.45 weeks in male participants (p < 0.0001). A relatively high proportion of female and male participants in this study reported premorbid diagnoses of depression and anxiety compared to general population characteristics.ConclusionAlthough premorbid diagnoses of depression and/or anxiety were associated with higher symptom burden at the initial visit, the duration of symptoms was not directly associated with a pre-injury history of psychological/psychiatric disturbance. This cohort of adults, from the general population, seeking care for their acute concussion attained clinical and functional recovery over a period of 4–12 weeks.https://www.frontiersin.org/articles/10.3389/fneur.2023.1152504/fullacute concussionmild TBIsex differencescharacteristicssymptom reporting |
| spellingShingle | Paul Comper Paul Comper Paul Comper Evan Foster Tharshini Chandra Laura Langer Catherine Wiseman-Hakes Catherine Wiseman-Hakes George Mochizuki George Mochizuki Lesley Ruttan Lesley Ruttan David W. Lawrence David W. Lawrence David W. Lawrence Elizabeth L. Inness Elizabeth L. Inness Elizabeth L. Inness Jonathan Gladstone Jonathan Gladstone Jonathan Gladstone Cristina Saverino Alan Tam Alan Tam Alice Kam Alice Kam Alice Kam Alice Kam Firas Al-Rawi Firas Al-Rawi Firas Al-Rawi Mark Theodore Bayley Mark Theodore Bayley The Toronto Concussion Study: a prospective investigation of characteristics in a cohort of adults from the general population seeking care following acute concussion, 2016–2020 Frontiers in Neurology acute concussion mild TBI sex differences characteristics symptom reporting |
| title | The Toronto Concussion Study: a prospective investigation of characteristics in a cohort of adults from the general population seeking care following acute concussion, 2016–2020 |
| title_full | The Toronto Concussion Study: a prospective investigation of characteristics in a cohort of adults from the general population seeking care following acute concussion, 2016–2020 |
| title_fullStr | The Toronto Concussion Study: a prospective investigation of characteristics in a cohort of adults from the general population seeking care following acute concussion, 2016–2020 |
| title_full_unstemmed | The Toronto Concussion Study: a prospective investigation of characteristics in a cohort of adults from the general population seeking care following acute concussion, 2016–2020 |
| title_short | The Toronto Concussion Study: a prospective investigation of characteristics in a cohort of adults from the general population seeking care following acute concussion, 2016–2020 |
| title_sort | toronto concussion study a prospective investigation of characteristics in a cohort of adults from the general population seeking care following acute concussion 2016 2020 |
| topic | acute concussion mild TBI sex differences characteristics symptom reporting |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1152504/full |
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